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Page 1
The rat bone marrow micronucleus test: Statistical considerations on historical negative control data.
Igl BW, Bitsch A, Bringezu F, Chang S, Dammann M, Frötschl R, Harm V, Kellner R, Krzykalla V, Lott J, Nern M, Pfuhler S, Queisser N, Schulz M, Sutter A, Vaas L, Vonk R, Zellner D, Ziemann C. Igl BW, et al. Among authors: pfuhler s. Regul Toxicol Pharmacol. 2019 Mar;102:13-22. doi: 10.1016/j.yrtph.2018.12.009. Epub 2018 Dec 17. Regul Toxicol Pharmacol. 2019. PMID: 30572081
Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing.
Guérard M, Baum M, Bitsch A, Eisenbrand G, Elhajouji A, Epe B, Habermeyer M, Kaina B, Martus HJ, Pfuhler S, Schmitz C, Sutter A, Thomas AD, Ziemann C, Froetschl R. Guérard M, et al. Among authors: pfuhler s. Mutat Res Rev Mutat Res. 2015 Jan-Mar;763:181-201. doi: 10.1016/j.mrrev.2014.11.001. Epub 2014 Nov 11. Mutat Res Rev Mutat Res. 2015. PMID: 25795120 Review.
Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility.
Reisinger K, Blatz V, Brinkmann J, Downs TR, Fischer A, Henkler F, Hoffmann S, Krul C, Liebsch M, Luch A, Pirow R, Reus AA, Schulz M, Pfuhler S. Reisinger K, et al. Among authors: pfuhler s. Mutat Res Genet Toxicol Environ Mutagen. 2018 Mar;827:27-41. doi: 10.1016/j.mrgentox.2018.01.003. Epub 2018 Jan 10. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 29502735 Free article.
A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.
Kirkland D, Levy DD, LeBaron MJ, Aardema MJ, Beevers C, Bhalli J, Douglas GR, Escobar PA, Farabaugh CS, Guerard M, Johnson GE, Kulkarni R, Le Curieux F, Long AS, Lott J, Lovell DP, Luijten M, Marchetti F, Nicolette JJ, Pfuhler S, Roberts DJ, Stankowski LF Jr, Thybaud V, Weiner SK, Williams A, Witt KL, Young R. Kirkland D, et al. Among authors: pfuhler s. Mutat Res Genet Toxicol Environ Mutagen. 2019 Mar;839:21-35. doi: 10.1016/j.mrgentox.2019.01.007. Epub 2019 Jan 18. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 30744809 Free PMC article.
A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: genotoxicity. A COLIPA analysis.
Pfuhler S, Kirst A, Aardema M, Banduhn N, Goebel C, Araki D, Costabel-Farkas M, Dufour E, Fautz R, Harvey J, Hewitt NJ, Hibatallah J, Carmichael P, Macfarlane M, Reisinger K, Rowland J, Schellauf F, Schepky A, Scheel J. Pfuhler S, et al. Regul Toxicol Pharmacol. 2010 Jul-Aug;57(2-3):315-24. doi: 10.1016/j.yrtph.2010.03.012. Epub 2010 Apr 9. Regul Toxicol Pharmacol. 2010. PMID: 20382194 Free article.
Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I. Reports of individual databases presented at an EURL ECVAM Workshop.
Kirkland D, Zeiger E, Madia F, Gooderham N, Kasper P, Lynch A, Morita T, Ouedraogo G, Parra Morte JM, Pfuhler S, Rogiers V, Schulz M, Thybaud V, van Benthem J, Vanparys P, Worth A, Corvi R. Kirkland D, et al. Among authors: pfuhler s. Mutat Res Genet Toxicol Environ Mutagen. 2014 Dec;775-776:55-68. doi: 10.1016/j.mrgentox.2014.10.005. Epub 2014 Oct 23. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 25435356 Free article.
A comparison of classical and 21st century genotoxicity tools: A proof of concept study of 18 chemicals comparing in vitro micronucleus, ToxTracker and genomics-based methods (TGx-DDI, whole genome clustering and connectivity mapping).
Allemang A, De Abrew KN, Shan YK, Krailler JM, Pfuhler S. Allemang A, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2021 Feb;62(2):92-107. doi: 10.1002/em.22418. Epub 2020 Dec 7. Environ Mol Mutagen. 2021. PMID: 33252785 Free PMC article.
75 results