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Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF.
Liang KL, Roels J, Lavaert M, Putteman T, Boehme L, Tilleman L, Velghe I, Pegoretti V, Van de Walle I, Sontag S, Vandewalle J, Vandekerckhove B, Leclercq G, Van Vlierberghe P, Libert C, Van Nieuwerburgh F, Fischer R, Kontermann RE, Pfizenmaier K, Doody G, Zenke M, Taghon T. Liang KL, et al. Among authors: pfizenmaier k. Nat Immunol. 2023 Mar;24(3):474-486. doi: 10.1038/s41590-022-01417-6. Epub 2023 Jan 26. Nat Immunol. 2023. PMID: 36703005 Free article.
Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis.
Fiedler T, Fairless R, Pichi K, Fischer R, Richter F, Kontermann RE, Pfizenmaier K, Diem R, Williams SK. Fiedler T, et al. Among authors: pfizenmaier k. J Neuroinflammation. 2023 Apr 30;20(1):100. doi: 10.1186/s12974-023-02784-z. J Neuroinflammation. 2023. PMID: 37122019 Free PMC article.
Tumor necrosis factor receptor 2 activation elicits sex-specific effects on cortical myelin proteins and functional recovery in a model of multiple sclerosis.
Nguyen KL, Bhatt IJ, Gupta S, Showkat N, Swanson KA, Fischer R, Kontermann RE, Pfizenmaier K, Bracchi-Ricard V, Bethea JR. Nguyen KL, et al. Among authors: pfizenmaier k. Brain Res Bull. 2024 Feb;207:110885. doi: 10.1016/j.brainresbull.2024.110885. Epub 2024 Jan 20. Brain Res Bull. 2024. PMID: 38246200 Free PMC article.
The TNFR1 Antagonist Atrosimab Is Therapeutic in Mouse Models of Acute and Chronic Inflammation.
Richter F, Williams SK, John K, Huber C, Vaslin C, Zanker H, Fairless R, Pichi K, Marhenke S, Vogel A, Dhaen MA, Herrmann S, Herrmann A, Pfizenmaier K, Bantel H, Diem R, Kontermann RE, Fischer R. Richter F, et al. Among authors: pfizenmaier k. Front Immunol. 2021 Jul 7;12:705485. doi: 10.3389/fimmu.2021.705485. eCollection 2021. Front Immunol. 2021. PMID: 34305946 Free PMC article.
Selective Targeting of TNF Receptors as a Novel Therapeutic Approach.
Fischer R, Kontermann RE, Pfizenmaier K. Fischer R, et al. Among authors: pfizenmaier k. Front Cell Dev Biol. 2020 May 26;8:401. doi: 10.3389/fcell.2020.00401. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32528961 Free PMC article. Review.
251 results