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The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia.
Czech B, Pfeilschifter W, Mazaheri-Omrani N, Strobel MA, Kahles T, Neumann-Haefelin T, Rami A, Huwiler A, Pfeilschifter J. Czech B, et al. Among authors: pfeilschifter w, pfeilschifter j. Biochem Biophys Res Commun. 2009 Nov 13;389(2):251-6. doi: 10.1016/j.bbrc.2009.08.142. Epub 2009 Aug 29. Biochem Biophys Res Commun. 2009. PMID: 19720050
FTY720 treatment in the convalescence period improves functional recovery and reduces reactive astrogliosis in photothrombotic stroke.
Brunkhorst R, Kanaan N, Koch A, Ferreirós N, Mirceska A, Zeiner P, Mittelbronn M, Derouiche A, Steinmetz H, Foerch C, Pfeilschifter J, Pfeilschifter W. Brunkhorst R, et al. Among authors: pfeilschifter w, pfeilschifter j. PLoS One. 2013 Jul 31;8(7):e70124. doi: 10.1371/journal.pone.0070124. Print 2013. PLoS One. 2013. PMID: 23936150 Free PMC article.
142 results