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CRISPR-Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells.
Lin-Shiao E, Pfeifer WG, Shy BR, Saffari Doost M, Chen E, Vykunta VS, Hamilton JR, Stahl EC, Lopez DM, Sandoval Espinoza CR, Deyanov AE, Lew RJ, Poirer MG, Marson A, Castro CE, Doudna JA. Lin-Shiao E, et al. Among authors: pfeifer wg. Nucleic Acids Res. 2022 Feb 22;50(3):1256-1268. doi: 10.1093/nar/gkac049. Nucleic Acids Res. 2022. PMID: 35104875 Free PMC article.
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails.
Shy BR, Vykunta VS, Ha A, Talbot A, Roth TL, Nguyen DN, Pfeifer WG, Chen YY, Blaeschke F, Shifrut E, Vedova S, Mamedov MR, Chung JJ, Li H, Yu R, Wu D, Wolf J, Martin TG, Castro CE, Ye L, Esensten JH, Eyquem J, Marson A. Shy BR, et al. Among authors: pfeifer wg. Nat Biotechnol. 2023 Apr;41(4):521-531. doi: 10.1038/s41587-022-01418-8. Epub 2022 Aug 25. Nat Biotechnol. 2023. PMID: 36008610 Free PMC article.
Piggybacking functionalized DNA nanostructures into live cell nuclei.
Roozbahani GM, Colosi P, Oravecz A, Sorokina EM, Pfeifer W, Shokri S, Wei Y, Didier P, DeLuca M, Arya G, Tora L, Lakadamyali M, Poirier MG, Castro CE. Roozbahani GM, et al. bioRxiv [Preprint]. 2024 Jan 1:2023.12.30.573746. doi: 10.1101/2023.12.30.573746. bioRxiv. 2024. PMID: 38260628 Free PMC article. Preprint.
12 results