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Gene immunization may induce secondary antibodies reacting with DNA.
Isaguliants MG, Iakimtchouk K, Petrakova NV, Yermalovich MA, Zuber AK, Kashuba VI, Belikov SV, Andersson S, Kochetkov SN, Klinman DM, Wahren B. Isaguliants MG, et al. Among authors: petrakova nv. Vaccine. 2004 Mar 29;22(11-12):1576-85. doi: 10.1016/j.vaccine.2003.09.033. Vaccine. 2004. PMID: 15063584
DNA immunization efficiently targets conserved functional domains of protease and ATPase/helicase of nonstructural 3 protein (NS3) of human hepatitis C virus.
Isaguliants MG, Petrakova NV, Mokhonov VV, Pokrovskaya K, Suzdaltzeva YG, Krivonos AV, Zaberezhny AD, Garaev MM, Smirnov VD, Nordenfelt E. Isaguliants MG, et al. Among authors: petrakova nv. Immunol Lett. 2003 Jul 3;88(1):1-13. doi: 10.1016/s0165-2478(03)00051-8. Immunol Lett. 2003. PMID: 12853154
Autoimmunogenicity of the helix-loop-helix DNA-binding domain.
Petrakova N, Gudmundsdotter L, Yermalovich M, Belikov S, Eriksson L, Pyakurel P, Johansson O, Biberfeld P, Andersson S, Isaguliants M. Petrakova N, et al. Mol Immunol. 2009 Apr;46(7):1467-80. doi: 10.1016/j.molimm.2008.12.013. Epub 2009 Jan 31. Mol Immunol. 2009. PMID: 19181386
Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, protein boost immunization regimen.
Alekseeva E, Sominskaya I, Skrastina D, Egorova I, Starodubova E, Kushners E, Mihailova M, Petrakova N, Bruvere R, Kozlovskaya T, Isaguliants M, Pumpens P. Alekseeva E, et al. Genet Vaccines Ther. 2009 Jun 8;7:7. doi: 10.1186/1479-0556-7-7. Genet Vaccines Ther. 2009. PMID: 19505299 Free PMC article.
22 results