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Multiple copies of the oxytetracycline gene cluster in selected Streptomyces rimosus strains can provide significantly increased titers.
Pikl Š, Carrillo Rincón AF, Slemc L, Goranovič D, Avbelj M, Gjuračić K, Sucipto H, Stare K, Baebler Š, Šala M, Guo M, Luzhetskyy A, Petković H, Magdevska V. Pikl Š, et al. Among authors: petkovic h. Microb Cell Fact. 2021 Feb 17;20(1):47. doi: 10.1186/s12934-021-01522-5. Microb Cell Fact. 2021. PMID: 33596911 Free PMC article.
Genetics of Streptomyces rimosus, the oxytetracycline producer.
Petković H, Cullum J, Hranueli D, Hunter IS, Perić-Concha N, Pigac J, Thamchaipenet A, Vujaklija D, Long PF. Petković H, et al. Microbiol Mol Biol Rev. 2006 Sep;70(3):704-28. doi: 10.1128/MMBR.00004-06. Microbiol Mol Biol Rev. 2006. PMID: 16959966 Free PMC article. Review.
Origin of the allyl group in FK506 biosynthesis.
Goranovic D, Kosec G, Mrak P, Fujs S, Horvat J, Kuscer E, Kopitar G, Petkovic H. Goranovic D, et al. Among authors: petkovic h. J Biol Chem. 2010 May 7;285(19):14292-300. doi: 10.1074/jbc.M109.059600. Epub 2010 Mar 1. J Biol Chem. 2010. PMID: 20194504 Free PMC article.
Novel chemobiosynthetic approach for exclusive production of FK506.
Kosec G, Goranovič D, Mrak P, Fujs S, Kuščer E, Horvat J, Kopitar G, Petković H. Kosec G, et al. Among authors: petkovic h. Metab Eng. 2012 Jan;14(1):39-46. doi: 10.1016/j.ymben.2011.11.003. Epub 2011 Nov 12. Metab Eng. 2012. PMID: 22100790
Annotation of the modular polyketide synthase and nonribosomal peptide synthetase gene clusters in the genome of Streptomyces tsukubaensis NRRL18488.
Blazic M, Starcevic A, Lisfi M, Baranasic D, Goranovic D, Fujs S, Kuscer E, Kosec G, Petkovic H, Cullum J, Hranueli D, Zucko J. Blazic M, et al. Among authors: petkovic h. Appl Environ Microbiol. 2012 Dec;78(23):8183-90. doi: 10.1128/AEM.01891-12. Epub 2012 Sep 14. Appl Environ Microbiol. 2012. PMID: 22983969 Free PMC article.
Identification of the chelocardin biosynthetic gene cluster from Amycolatopsis sulphurea: a platform for producing novel tetracycline antibiotics.
Lukežič T, Lešnik U, Podgoršek A, Horvat J, Polak T, Šala M, Jenko B, Raspor P, Herron PR, Hunter IS, Petković H. Lukežič T, et al. Among authors: petkovic h. Microbiology (Reading). 2013 Dec;159(Pt 12):2524-2532. doi: 10.1099/mic.0.070995-0. Epub 2013 Sep 16. Microbiology (Reading). 2013. PMID: 24043447 Free article.
SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea.
Kirm B, Magdevska V, Tome M, Horvat M, Karničar K, Petek M, Vidmar R, Baebler S, Jamnik P, Fujs Š, Horvat J, Fonovič M, Turk B, Gruden K, Petković H, Kosec G. Kirm B, et al. Among authors: petkovic h. Microb Cell Fact. 2013 Dec 17;12:126. doi: 10.1186/1475-2859-12-126. Microb Cell Fact. 2013. PMID: 24341557 Free PMC article.
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