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T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.
Arunachalam PS, Charles TP, Joag V, Bollimpelli VS, Scott MKD, Wimmers F, Burton SL, Labranche CC, Petitdemange C, Gangadhara S, Styles TM, Quarnstrom CF, Walter KA, Ketas TJ, Legere T, Jagadeesh Reddy PB, Kasturi SP, Tsai A, Yeung BZ, Gupta S, Tomai M, Vasilakos J, Shaw GM, Kang CY, Moore JP, Subramaniam S, Khatri P, Montefiori D, Kozlowski PA, Derdeyn CA, Hunter E, Masopust D, Amara RR, Pulendran B. Arunachalam PS, et al. Among authors: petitdemange c. Nat Med. 2020 Jun;26(6):932-940. doi: 10.1038/s41591-020-0858-8. Epub 2020 May 11. Nat Med. 2020. PMID: 32393800 Free PMC article.
Vaccine induction of antibodies and tissue-resident CD8+ T cells enhances protection against mucosal SHIV-infection in young macaques.
Petitdemange C, Kasturi SP, Kozlowski PA, Nabi R, Quarnstrom CF, Reddy PBJ, Derdeyn CA, Spicer LM, Patel P, Legere T, Kovalenkov YO, Labranche CC, Villinger F, Tomai M, Vasilakos J, Haynes B, Kang CY, Gibbs JS, Yewdell JW, Barouch D, Wrammert J, Montefiori D, Hunter E, Amara RR, Masopust D, Pulendran B. Petitdemange C, et al. JCI Insight. 2019 Feb 21;4(4):e126047. doi: 10.1172/jci.insight.126047. eCollection 2019 Feb 21. JCI Insight. 2019. PMID: 30830870 Free PMC article.
Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans.
Hagan T, Cortese M, Rouphael N, Boudreau C, Linde C, Maddur MS, Das J, Wang H, Guthmiller J, Zheng NY, Huang M, Uphadhyay AA, Gardinassi L, Petitdemange C, McCullough MP, Johnson SJ, Gill K, Cervasi B, Zou J, Bretin A, Hahn M, Gewirtz AT, Bosinger SE, Wilson PC, Li S, Alter G, Khurana S, Golding H, Pulendran B. Hagan T, et al. Among authors: petitdemange c. Cell. 2019 Sep 5;178(6):1313-1328.e13. doi: 10.1016/j.cell.2019.08.010. Cell. 2019. PMID: 31491384 Free PMC article. Clinical Trial.
SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity.
Huot N, Rascle P, Petitdemange C, Contreras V, Stürzel CM, Baquero E, Harper JL, Passaes C, Legendre R, Varet H, Madec Y, Sauermann U, Stahl-Hennig C, Nattermann J, Saez-Cirion A, Le Grand R, Keith Reeves R, Paiardini M, Kirchhoff F, Jacquelin B, Müller-Trutwin M. Huot N, et al. Among authors: petitdemange c. Nat Commun. 2021 Feb 24;12(1):1282. doi: 10.1038/s41467-021-21402-1. Nat Commun. 2021. PMID: 33627642 Free PMC article.
SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells.
Huot N, Planchais C, Rosenbaum P, Contreras V, Jacquelin B, Petitdemange C, Lazzerini M, Beaumont E, Orta-Resendiz A, Rey FA, Reeves RK, Le Grand R, Mouquet H, Müller-Trutwin M. Huot N, et al. Among authors: petitdemange c. Nat Immunol. 2023 Dec;24(12):2068-2079. doi: 10.1038/s41590-023-01661-4. Epub 2023 Nov 2. Nat Immunol. 2023. PMID: 37919524 Free PMC article.
Interests of the Non-Human Primate Models for HIV Cure Research.
Terrade G, Huot N, Petitdemange C, Lazzerini M, Orta Resendiz A, Jacquelin B, Müller-Trutwin M. Terrade G, et al. Among authors: petitdemange c. Vaccines (Basel). 2021 Aug 27;9(9):958. doi: 10.3390/vaccines9090958. Vaccines (Basel). 2021. PMID: 34579195 Free PMC article. Review.
A recombinant measles virus vaccine strongly reduces SHIV viremia and virus reservoir establishment in macaques.
Nzounza P, Martin G, Dereuddre-Bosquet N, Najburg V, Gosse L, Ruffié C, Combredet C, Petitdemange C, Souquère S, Schlecht-Louf G, Moog C, Pierron G, Le Grand R, Heidmann T, Tangy F. Nzounza P, et al. Among authors: petitdemange c. NPJ Vaccines. 2021 Oct 22;6(1):123. doi: 10.1038/s41541-021-00385-6. NPJ Vaccines. 2021. PMID: 34686669 Free PMC article.
22 results