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GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876.
Ragunathan P, Shuyi Ng P, Singh S, Poh WH, Litty D, Kalia NP, Larsson S, Harikishore A, Rice SA, Ingham PW, Müller V, Moraski G, Miller MJ, Dick T, Pethe K, Grüber G. Ragunathan P, et al. Among authors: pethe k. Microbiol Spectr. 2023 Dec 12;11(6):e0228223. doi: 10.1128/spectrum.02282-23. Epub 2023 Nov 20. Microbiol Spectr. 2023. PMID: 37982630 Free PMC article.
Sensitive profiling of chemically diverse bioactive lipids.
Shui G, Bendt AK, Pethe K, Dick T, Wenk MR. Shui G, et al. Among authors: pethe k. J Lipid Res. 2007 Sep;48(9):1976-84. doi: 10.1194/jlr.M700060-JLR200. Epub 2007 Jun 12. J Lipid Res. 2007. PMID: 17565170 Free article.
Discovery of a Novel Mycobacterial F-ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines.
Hotra A, Ragunathan P, Ng PS, Seankongsuk P, Harikishore A, Sarathy JP, Saw WG, Lakshmanan U, Sae-Lao P, Kalia NP, Shin J, Kalyanasundaram R, Anbarasu S, Parthasarathy K, Pradeep CN, Makhija H, Dröge P, Poulsen A, Tan JHL, Pethe K, Dick T, Bates RW, Grüber G. Hotra A, et al. Among authors: pethe k. Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13295-13304. doi: 10.1002/anie.202002546. Epub 2020 May 26. Angew Chem Int Ed Engl. 2020. PMID: 32337801
Toward a Single-Dose Cure for Buruli Ulcer.
Thomas SS, Kalia NP, Ruf MT, Pluschke G, Pethe K. Thomas SS, et al. Among authors: pethe k. Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00727-20. doi: 10.1128/AAC.00727-20. Print 2020 Aug 20. Antimicrob Agents Chemother. 2020. PMID: 32631818 Free PMC article.
Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis.
Lee BS, Hards K, Engelhart CA, Hasenoehrl EJ, Kalia NP, Mackenzie JS, Sviriaeva E, Chong SMS, Manimekalai MSS, Koh VH, Chan J, Xu J, Alonso S, Miller MJ, Steyn AJC, Grüber G, Schnappinger D, Berney M, Cook GM, Moraski GC, Pethe K. Lee BS, et al. Among authors: pethe k. EMBO Mol Med. 2021 Jan 11;13(1):e13207. doi: 10.15252/emmm.202013207. Epub 2020 Dec 7. EMBO Mol Med. 2021. PMID: 33283973 Free PMC article.
120 results