Peter R. Young - Search Results

Year	Number of Results
2002	6
2003	3
2004	1
2006	2
2007	1
2011	1
2012	2
2013	2
2014	2
2015	2
2016	2
2017	1
2018	1
2019	2
2024	1

1

Apilimod dimesylate in C9orf72 amyotrophic lateral sclerosis: a randomized phase 2a clinical trial.

Babu S, Nicholson KA, Rothstein JD, Swenson A, Sampognaro PJ, Pant P, Macklin EA, Spruill S, Paganoni S, Gendron TF, Prudencio M, Petrucelli L, Nix D, Landrette S, Nkrumah E, Fandrick K, Edwards J, Young PR. Babu S, et al. Among authors: young pr. Brain. 2024 Apr 12:awae109. doi: 10.1093/brain/awae109. Online ahead of print. Brain. 2024. PMID: 38606777

2

LAM-003, a new drug for treatment of tyrosine kinase inhibitor-resistant FLT3-ITD-positive AML.

Beeharry N, Landrette S, Gayle S, Hernandez M, Grotzke JE, Young PR, Beckett P, Zhang X, Carter BZ, Andreeff M, Halene S, Xu T, Rothberg J, Lichenstein H. Beeharry N, et al. Among authors: young pr. Blood Adv. 2019 Nov 26;3(22):3661-3673. doi: 10.1182/bloodadvances.2019001068. Blood Adv. 2019. PMID: 31751472 Free PMC article.

3

The Sun: Our own backyard plasma laboratory.

Young PR. Young PR. Proc Int Astron Union. 2019 Apr;15(Suppl 350):333-340. doi: 10.1017/s1743921319008366. Epub 2020 Oct 12. Proc Int Astron Union. 2019. PMID: 33294002 Free PMC article.

4

Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine.

Kharenko OA, Patel RG, Brown SD, Calosing C, White A, Lakshminarasimhan D, Suto RK, Duffy BC, Kitchen DB, McLure KG, Hansen HC, van der Horst EH, Young PR. Kharenko OA, et al. Among authors: young pr. J Med Chem. 2018 Sep 27;61(18):8202-8211. doi: 10.1021/acs.jmedchem.8b00666. Epub 2018 Sep 13. J Med Chem. 2018. PMID: 30165024

5

RVX-297, a BET Bromodomain Inhibitor, Has Therapeutic Effects in Preclinical Models of Acute Inflammation and Autoimmune Disease.

Jahagirdar R, Attwell S, Marusic S, Bendele A, Shenoy N, McLure KG, Gilham D, Norek K, Hansen HC, Yu R, Tobin J, Wagner GS, Young PR, Wong NCW, Kulikowski E. Jahagirdar R, et al. Among authors: young pr. Mol Pharmacol. 2017 Dec;92(6):694-706. doi: 10.1124/mol.117.110379. Epub 2017 Sep 29. Mol Pharmacol. 2017. PMID: 28974538

6

Data on gene and protein expression changes induced by apabetalone (RVX-208) in ex vivo treated human whole blood and primary hepatocytes.

Wasiak S, Gilham D, Tsujikawa LM, Halliday C, Norek K, Patel RG, McLure KG, Young PR, Gordon A, Kulikowski E, Johansson J, Sweeney M, Wong NC. Wasiak S, et al. Among authors: young pr. Data Brief. 2016 Jul 29;8:1280-8. doi: 10.1016/j.dib.2016.07.047. eCollection 2016 Sep. Data Brief. 2016. PMID: 27570805 Free PMC article.

7

RVX-297- a novel BD2 selective inhibitor of BET bromodomains.

Kharenko OA, Gesner EM, Patel RG, Norek K, White A, Fontano E, Suto RK, Young PR, McLure KG, Hansen HC. Kharenko OA, et al. Among authors: young pr. Biochem Biophys Res Commun. 2016 Aug 12;477(1):62-67. doi: 10.1016/j.bbrc.2016.06.021. Epub 2016 Jun 6. Biochem Biophys Res Commun. 2016. PMID: 27282480

8

Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.

Duffy BC, Liu S, Martin GS, Wang R, Hsia MM, Zhao H, Guo C, Ellis M, Quinn JF, Kharenko OA, Norek K, Gesner EM, Young PR, McLure KG, Wagner GS, Lakshminarasimhan D, White A, Suto RK, Hansen HC, Kitchen DB. Duffy BC, et al. Among authors: young pr. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2818-23. doi: 10.1016/j.bmcl.2015.04.107. Epub 2015 May 11. Bioorg Med Chem Lett. 2015. PMID: 26022843

9

RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development.

Verma R, Su S, McCrann DJ, Green JM, Leu K, Young PR, Schatz PJ, Silva JC, Stokes MP, Wojchowski DM. Verma R, et al. Among authors: young pr. J Exp Med. 2015 Jun 1;212(6):971. doi: 10.1084/jem.2013062404242015c. Epub 2015 May 4. J Exp Med. 2015. PMID: 25941257 Free PMC article. No abstract available.

10

RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development.

Verma R, Su S, McCrann DJ, Green JM, Leu K, Young PR, Schatz PJ, Silva JC, Stokes MP, Wojchowski DM. Verma R, et al. Among authors: young pr. J Exp Med. 2014 Aug 25;211(9):1715-22. doi: 10.1084/jem.20130624. Epub 2014 Aug 4. J Exp Med. 2014. PMID: 25092874 Free PMC article.

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