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Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1.
Espinosa-Bustos C, Lagos CF, Romero-Parra J, Zárate AM, Mella-Raipán J, Pessoa-Mahana H, Recabarren-Gajardo G, Iturriaga-Vásquez P, Tapia RA, Pessoa-Mahana CD. Espinosa-Bustos C, et al. Arch Pharm (Weinheim). 2015 Feb;348(2):81-8. doi: 10.1002/ardp.201400201. Epub 2015 Jan 13. Arch Pharm (Weinheim). 2015. PMID: 25641513
Synthesis and Docking of Novel 3-Indolylpropyl Derivatives as New Polypharmacological Agents Displaying Affinity for 5-HT1A R/SERT.
Pessoa-Mahana H, Silva-Matus P, Pessoa-Mahana CD, Chung H, Iturriaga-Vásquez P, Quiroz G, Möller-Acuña P, Zapata-Torres G, Saitz-Barría C, Araya-Maturana R, Reyes-Parada M. Pessoa-Mahana H, et al. Among authors: pessoa mahana cd. Arch Pharm (Weinheim). 2017 Jan;350(1). doi: 10.1002/ardp.201600271. Epub 2016 Dec 16. Arch Pharm (Weinheim). 2017. PMID: 27981607
Synthesis and biological evaluation of potential acetylcholinesterase inhibitors based on a benzoxazine core.
Méndez-Rojas C, Quiroz G, Faúndez M, Gallardo-Garrido C, Pessoa-Mahana CD, Chung H, Gallardo-Toledo E, Saitz-Barría C, Araya-Maturana R, Kogan MJ, Zúñiga-López MC, Iturriaga-Vásquez P, Valenzuela-Gutiérrez C, Pessoa-Mahana H. Méndez-Rojas C, et al. Among authors: pessoa mahana cd. Arch Pharm (Weinheim). 2018 May;351(5):e1800024. doi: 10.1002/ardp.201800024. Epub 2018 Apr 3. Arch Pharm (Weinheim). 2018. PMID: 29611620
Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands.
Lorca M, Valdes Y, Chung H, Romero-Parra J, Pessoa-Mahana CD, Mella J. Lorca M, et al. Among authors: pessoa mahana cd. Int J Mol Sci. 2019 May 21;20(10):2510. doi: 10.3390/ijms20102510. Int J Mol Sci. 2019. PMID: 31117309 Free PMC article.
23 results