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Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response.
Henriksen-Lacey M, Christensen D, Bramwell VW, Lindenstrøm T, Agger EM, Andersen P, Perrie Y. Henriksen-Lacey M, et al. Among authors: perrie y. J Control Release. 2010 Jul 14;145(2):102-8. doi: 10.1016/j.jconrel.2010.03.027. Epub 2010 Apr 8. J Control Release. 2010. PMID: 20381556
The impact of ageing on the barriers to drug delivery.
Perrie Y, Badhan RK, Kirby DJ, Lowry D, Mohammed AR, Ouyang D. Perrie Y, et al. J Control Release. 2012 Jul 20;161(2):389-98. doi: 10.1016/j.jconrel.2012.01.020. Epub 2012 Jan 24. J Control Release. 2012. PMID: 22289435 Review.
A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog.
Christensen D, Henriksen-Lacey M, Kamath AT, Lindenstrøm T, Korsholm KS, Christensen JP, Rochat AF, Lambert PH, Andersen P, Siegrist CA, Perrie Y, Agger EM. Christensen D, et al. Among authors: perrie y. J Control Release. 2012 Jun 28;160(3):468-76. doi: 10.1016/j.jconrel.2012.03.016. Epub 2012 Mar 27. J Control Release. 2012. PMID: 22709414
157 results