Perlmutter D - Search Results

1

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance.

Singh I, Sagare AP, Coma M, Perlmutter D, Gelein R, Bell RD, Deane RJ, Zhong E, Parisi M, Ciszewski J, Kasper RT, Deane R. Singh I, et al. Among authors: perlmutter d. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14771-6. doi: 10.1073/pnas.1302212110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959870 Free PMC article.

2

Clearance of amyloid-beta by circulating lipoprotein receptors.

Sagare A, Deane R, Bell RD, Johnson B, Hamm K, Pendu R, Marky A, Lenting PJ, Wu Z, Zarcone T, Goate A, Mayo K, Perlmutter D, Coma M, Zhong Z, Zlokovic BV. Sagare A, et al. Among authors: perlmutter d. Nat Med. 2007 Sep;13(9):1029-31. doi: 10.1038/nm1635. Epub 2007 Aug 12. Nat Med. 2007. PMID: 17694066 Free PMC article.

3

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration.

Winkler EA, Nishida Y, Sagare AP, Rege SV, Bell RD, Perlmutter D, Sengillo JD, Hillman S, Kong P, Nelson AR, Sullivan JS, Zhao Z, Meiselman HJ, Wendy RB, Soto J, Abel ED, Makshanoff J, Zuniga E, De Vivo DC, Zlokovic BV. Winkler EA, et al. Among authors: perlmutter d. Nat Neurosci. 2015 Apr;18(4):521-530. doi: 10.1038/nn.3966. Epub 2015 Mar 2. Nat Neurosci. 2015. PMID: 25730668 Free PMC article.

4

A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency.

Wu Y, Whitman I, Molmenti E, Moore K, Hippenmeyer P, Perlmutter DH. Wu Y, et al. Among authors: perlmutter dh. Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):9014-8. doi: 10.1073/pnas.91.19.9014. Proc Natl Acad Sci U S A. 1994. PMID: 8090762 Free PMC article.

5

Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency.

Burrows JA, Willis LK, Perlmutter DH. Burrows JA, et al. Among authors: perlmutter dh. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1796-801. doi: 10.1073/pnas.97.4.1796. Proc Natl Acad Sci U S A. 2000. PMID: 10677536 Free PMC article.

6

Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes.

Ding J, Yannam GR, Roy-Chowdhury N, Hidvegi T, Basma H, Rennard SI, Wong RJ, Avsar Y, Guha C, Perlmutter DH, Fox IJ, Roy-Chowdhury J. Ding J, et al. J Clin Invest. 2011 May;121(5):1930-4. doi: 10.1172/JCI45260. Epub 2011 Apr 18. J Clin Invest. 2011. PMID: 21505264 Free PMC article.

7

Functions of autophagy in normal and diseased liver.

Czaja MJ, Ding WX, Donohue TM Jr, Friedman SL, Kim JS, Komatsu M, Lemasters JJ, Lemoine A, Lin JD, Ou JH, Perlmutter DH, Randall G, Ray RB, Tsung A, Yin XM. Czaja MJ, et al. Among authors: perlmutter dh. Autophagy. 2013 Aug;9(8):1131-58. doi: 10.4161/auto.25063. Epub 2013 May 22. Autophagy. 2013. PMID: 23774882 Free PMC article. Review.

8

Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.

Perlmutter DH, Cole FS, Kilbridge P, Rossing TH, Colten HR. Perlmutter DH, et al. Proc Natl Acad Sci U S A. 1985 Feb;82(3):795-9. doi: 10.1073/pnas.82.3.795. Proc Natl Acad Sci U S A. 1985. PMID: 3871944 Free PMC article.

9

Preventing Alzheimer's Disease.

Perlmutter D. Perlmutter D. J Am Coll Nutr. 2016 Nov-Dec;35(8):732-733. doi: 10.1080/07315724.2015.1116900. Epub 2016 Nov 2. J Am Coll Nutr. 2016. PMID: 27805480 No abstract available.

10

Evidence for an acute phase response in human intestinal epithelial cells.

Molmenti EP, Ziambaras T, Perlmutter DH. Molmenti EP, et al. Among authors: perlmutter dh. J Biol Chem. 1993 Jul 5;268(19):14116-24. J Biol Chem. 1993. PMID: 7686149 Free article.

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