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A 6-month inhalation toxicology study in Apoe-/- mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.
Wong ET, Szostak J, Titz B, Lee T, Wong SK, Lavrynenko O, Merg C, Corciulo M, Simicevic J, Auberson M, Peric D, Dulize R, Bornand D, Loh GJ, Lee KM, Zhang J, Miller JH 4th, Schlage WK, Guedj E, Schneider T, Phillips B, Leroy P, Choukrallah MA, Sierro N, Buettner A, Xiang Y, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Wong ET, et al. Among authors: peric d. Arch Toxicol. 2021 May;95(5):1805-1829. doi: 10.1007/s00204-021-03020-4. Epub 2021 May 7. Arch Toxicol. 2021. PMID: 33963423 Free PMC article.
In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette.
Gonzalez-Suarez I, Martin F, Marescotti D, Guedj E, Acali S, Johne S, Dulize R, Baumer K, Peric D, Goedertier D, Frentzel S, Ivanov NV, Mathis C, Hoeng J, Peitsch MC. Gonzalez-Suarez I, et al. Among authors: peric d. Chem Res Toxicol. 2016 Jan 19;29(1):3-18. doi: 10.1021/acs.chemrestox.5b00321. Epub 2015 Dec 29. Chem Res Toxicol. 2016. PMID: 26651182
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.
Titz B, Kogel U, Martin F, Schlage WK, Xiang Y, Nury C, Dijon S, Baumer K, Peric D, Bornand D, Dulize R, Phillips B, Leroy P, Vuillaume G, Lebrun S, Elamin A, Guedj E, Trivedi K, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J. Titz B, et al. Among authors: peric d. Food Chem Toxicol. 2018 May;115:284-301. doi: 10.1016/j.fct.2018.02.058. Epub 2018 Mar 13. Food Chem Toxicol. 2018. PMID: 29545142 Free article.
In vitro systems toxicology-based assessment of the potential modified risk tobacco product CHTP 1.2 for vascular inflammation- and cytotoxicity-associated mechanisms promoting adhesion of monocytic cells to human coronary arterial endothelial cells.
Poussin C, Laurent A, Kondylis A, Marescotti D, van der Toorn M, Guedj E, Goedertier D, Acali S, Pak C, Dulize R, Baumer K, Peric D, Maluenda E, Bornand D, Suarez IG, Schlage WK, Ivanov NV, Peitsch MC, Hoeng J. Poussin C, et al. Among authors: peric d. Food Chem Toxicol. 2018 Oct;120:390-406. doi: 10.1016/j.fct.2018.07.025. Epub 2018 Jul 17. Food Chem Toxicol. 2018. PMID: 30026091 Free article.
How complex should an in vitro model be? Evaluation of complex 3D alveolar model with transcriptomic data and computational biological network models.
Marescotti D, Serchi T, Luettich K, Xiang Y, Moschini E, Talikka M, Martin F, Baumer K, Dulize R, Peric D, Bornand D, Guedj E, Sewer A, Cambier S, Contal S, Chary A, Gutleb AC, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J. Marescotti D, et al. Among authors: peric d. ALTEX. 2019;36(3):388-402. doi: 10.14573/altex.1811221. Epub 2019 Feb 12. ALTEX. 2019. PMID: 30753736 Free article.
Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells.
Marescotti D, Mathis C, Belcastro V, Leroy P, Acali S, Martin F, Dulize R, Bornand D, Peric D, Guedj E, Ortega Torres L, Biasioli M, Fuhrimann M, Fernandes E, Frauendorfer F, Gonzalez Suarez I, Sciuscio D, Ivanov NV, Peitsch MC, Hoeng J. Marescotti D, et al. Among authors: peric d. Toxicol Rep. 2019 Nov 25;7:67-80. doi: 10.1016/j.toxrep.2019.11.016. eCollection 2020. Toxicol Rep. 2019. PMID: 31886136 Free PMC article.
The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts.
Lo Sasso G, Phillips BW, Sewer A, Battey JND, Kondylis A, Talikka M, Titz B, Guedj E, Peric D, Bornand D, Dulize R, Merg C, Corciulo M, Ouadi S, Yanuar R, Tung CK, Ivanov NV, Peitsch MC, Hoeng J. Lo Sasso G, et al. Among authors: peric d. Sci Rep. 2020 Mar 2;10(1):3829. doi: 10.1038/s41598-020-60175-3. Sci Rep. 2020. PMID: 32123204 Free PMC article.
Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis.
Ruiz Castro PA, Kogel U, Lo Sasso G, Phillips BW, Sewer A, Titz B, Garcia L, Kondylis A, Guedj E, Peric D, Bornand D, Dulize R, Merg C, Corciulo M, Ivanov NV, Peitsch MC, Hoeng J. Ruiz Castro PA, et al. Among authors: peric d. J Inflamm (Lond). 2020 Aug 24;17:29. doi: 10.1186/s12950-020-00260-6. eCollection 2020. J Inflamm (Lond). 2020. PMID: 32855621 Free PMC article.
A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products.
Sewer A, Zanetti F, Iskandar AR, Guedj E, Dulize R, Peric D, Bornand D, Mathis C, Martin F, Ivanov NV, Peitsch MC, Hoeng J. Sewer A, et al. Among authors: peric d. Toxicol Rep. 2020 Sep 12;7:1282-1295. doi: 10.1016/j.toxrep.2020.09.001. eCollection 2020. Toxicol Rep. 2020. PMID: 33014713 Free PMC article.
57 results