Perelló J - Search Results

1

A novel assay to measure calcification propensity: from laboratory to humans.

Perez MM, Ferrer MD, Lazo-Rodriguez M, Canals AZ, Banon-Maneus E, Campistol JM, Miller S, Garg R, Gold A, Salcedo C, Perelló J. Perez MM, et al. Among authors: perello j. Sci Rep. 2020 Oct 16;10(1):17578. doi: 10.1038/s41598-020-74592-x. Sci Rep. 2020. PMID: 33067536 Free PMC article.

2

Hypothesis: Phytate is an important unrecognised nutrient and potential intravenous drug for preventing vascular calcification.

Joubert P, Ketteler M, Salcedo C, Perello J. Joubert P, et al. Among authors: perello j. Med Hypotheses. 2016 Sep;94:89-92. doi: 10.1016/j.mehy.2016.07.005. Epub 2016 Jul 12. Med Hypotheses. 2016. PMID: 27515210

3

A novel pharmacodynamic assay to evaluate the effects of crystallization inhibitors on calcium phosphate crystallization in human plasma.

Ferrer MD, Pérez MM, Cànaves MM, Buades JM, Salcedo C, Perelló J. Ferrer MD, et al. Among authors: perello j. Sci Rep. 2017 Jul 31;7(1):6858. doi: 10.1038/s41598-017-07203-x. Sci Rep. 2017. PMID: 28761091 Free PMC article.

4

SNF472, a novel inhibitor of vascular calcification, could be administered during hemodialysis to attain potentially therapeutic phytate levels.

Perelló J, Gómez M, Ferrer MD, Rodríguez NY, Salcedo C, Buades JM, Pérez MM, Torregrosa JV, Martín E, Maduell F. Perelló J, et al. J Nephrol. 2018 Apr;31(2):287-296. doi: 10.1007/s40620-018-0471-9. Epub 2018 Jan 19. J Nephrol. 2018. PMID: 29350348 Free PMC article.

5

Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification.

Ferrer MD, Ketteler M, Tur F, Tur E, Isern B, Salcedo C, Joubert PH, Behets GJ, Neven E, D'Haese PC, Perelló J. Ferrer MD, et al. Among authors: perello j. PLoS One. 2018 May 9;13(5):e0197061. doi: 10.1371/journal.pone.0197061. eCollection 2018. PLoS One. 2018. PMID: 29742152 Free PMC article.

6

First-time-in-human randomized clinical trial in healthy volunteers and haemodialysis patients with SNF472, a novel inhibitor of vascular calcification.

Perelló J, Joubert PH, Ferrer MD, Canals AZ, Sinha S, Salcedo C. Perelló J, et al. Br J Clin Pharmacol. 2018 Dec;84(12):2867-2876. doi: 10.1111/bcp.13752. Epub 2018 Oct 3. Br J Clin Pharmacol. 2018. PMID: 30280390 Free PMC article. Clinical Trial.

7

A phase 1b randomized, placebo-controlled clinical trial with SNF472 in haemodialysis patients.

Salcedo C, Joubert PH, Ferrer MD, Canals AZ, Maduell F, Torregrosa V, Campistol JM, Ojeda R, Perelló J. Salcedo C, et al. Among authors: perello j. Br J Clin Pharmacol. 2019 Apr;85(4):796-806. doi: 10.1111/bcp.13863. Epub 2019 Feb 19. Br J Clin Pharmacol. 2019. PMID: 30632182 Free PMC article. Clinical Trial.

8

Improvement in wound healing, pain, and quality of life after 12 weeks of SNF472 treatment: a phase 2 open-label study of patients with calciphylaxis.

Brandenburg VM, Sinha S, Torregrosa JV, Garg R, Miller S, Canals AZ, Bahr D, Joubert PH, Salcedo C, Carroll KJ, Gold A, Perelló J. Brandenburg VM, et al. Among authors: perello j. J Nephrol. 2019 Oct;32(5):811-821. doi: 10.1007/s40620-019-00631-0. Epub 2019 Aug 10. J Nephrol. 2019. PMID: 31401795 Clinical Trial.

9

SNF472, a novel anti-crystallization agent, inhibits induced calcification in an in vitro model of human aortic valve calcification.

Zabirnyk A, Ferrer MD, Bogdanova M, Pérez MM, Salcedo C, Kaljusto ML, Kvitting JP, Stensløkken KO, Perelló J, Vaage J. Zabirnyk A, et al. Among authors: perello j. Vascul Pharmacol. 2019 Nov-Dec;122-123:106583. doi: 10.1016/j.vph.2019.106583. Epub 2019 Aug 19. Vascul Pharmacol. 2019. PMID: 31437530 Free article.

10

Slowing Progression of Cardiovascular Calcification With SNF472 in Patients on Hemodialysis: Results of a Randomized Phase 2b Study.

Raggi P, Bellasi A, Bushinsky D, Bover J, Rodriguez M, Ketteler M, Sinha S, Salcedo C, Gillotti K, Padgett C, Garg R, Gold A, Perelló J, Chertow GM. Raggi P, et al. Among authors: perello j. Circulation. 2020 Mar 3;141(9):728-739. doi: 10.1161/CIRCULATIONAHA.119.044195. Epub 2019 Nov 11. Circulation. 2020. PMID: 31707860 Free article. Clinical Trial.

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