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Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease.
Luukkonen PK, Qadri S, Ahlholm N, Porthan K, Männistö V, Sammalkorpi H, Penttilä AK, Hakkarainen A, Lehtimäki TE, Gaggini M, Gastaldelli A, Ala-Korpela M, Orho-Melander M, Arola J, Juuti A, Pihlajamäki J, Hodson L, Yki-Järvinen H. Luukkonen PK, et al. Among authors: penttila ak. J Hepatol. 2022 Mar;76(3):526-535. doi: 10.1016/j.jhep.2021.10.013. Epub 2021 Oct 25. J Hepatol. 2022. PMID: 34710482 Free PMC article.
The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue.
Qadri S, Lallukka-Brück S, Luukkonen PK, Zhou Y, Gastaldelli A, Orho-Melander M, Sammalkorpi H, Juuti A, Penttilä AK, Perttilä J, Hakkarainen A, Lehtimäki TE, Orešič M, Hyötyläinen T, Hodson L, Olkkonen VM, Yki-Järvinen H. Qadri S, et al. Among authors: penttila ak. Liver Int. 2020 Sep;40(9):2128-2138. doi: 10.1111/liv.14507. Epub 2020 May 18. Liver Int. 2020. PMID: 32386450
Obesity Modifies the Performance of Fibrosis Biomarkers in Nonalcoholic Fatty Liver Disease.
Qadri S, Ahlholm N, Lønsmann I, Pellegrini P, Poikola A, Luukkonen PK, Porthan K, Juuti A, Sammalkorpi H, Penttilä AK, D'Ambrosio R, Soardo G, Leeming DJ, Karsdal M, Arola J, Kechagias S, Pelusi S, Ekstedt M, Valenti L, Hagström H, Yki-Järvinen H. Qadri S, et al. Among authors: penttila ak. J Clin Endocrinol Metab. 2022 Apr 19;107(5):e2008-e2020. doi: 10.1210/clinem/dgab933. J Clin Endocrinol Metab. 2022. PMID: 34971370 Free PMC article.
Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis.
Luukkonen PK, Sakuma I, Gaspar RC, Mooring M, Nasiri A, Kahn M, Zhang XM, Zhang D, Sammalkorpi H, Penttilä AK, Orho-Melander M, Arola J, Juuti A, Zhang X, Yimlamai D, Yki-Järvinen H, Petersen KF, Shulman GI. Luukkonen PK, et al. Among authors: penttila ak. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217543120. doi: 10.1073/pnas.2217543120. Epub 2023 Jan 20. Proc Natl Acad Sci U S A. 2023. PMID: 36669104 Free PMC article.
Human visceral adipose tissue microvascular endothelial cell isolation and establishment of co-culture with white adipocytes to analyze cell-cell communication.
Chaurasiya V, Pham DD, Harju J, Juuti A, Penttilä A, Emmagouni SKG, Nguyen VD, Zhang B, Perttunen S, Keskitalo S, Zhou Y, Pietiläinen KH, Haridas PAN, Olkkonen VM. Chaurasiya V, et al. Exp Cell Res. 2023 Dec 15;433(2):113819. doi: 10.1016/j.yexcr.2023.113819. Epub 2023 Oct 16. Exp Cell Res. 2023. PMID: 37852349
20 results