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The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM. Cronin SJF, et al. Among authors: penninger jm. Nature. 2018 Nov;563(7732):564-568. doi: 10.1038/s41586-018-0701-2. Epub 2018 Nov 7. Nature. 2018. PMID: 30405245 Free PMC article.
Negative regulation of T cell receptor signals.
Rangachari M, Penninger JM. Rangachari M, et al. Among authors: penninger jm. Curr Opin Pharmacol. 2004 Aug;4(4):415-22. doi: 10.1016/j.coph.2004.03.007. Curr Opin Pharmacol. 2004. PMID: 15251138 Review.
Angiotensin-converting enzyme 2 protects from severe acute lung failure.
Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C, Penninger JM. Imai Y, et al. Among authors: penninger jm. Nature. 2005 Jul 7;436(7047):112-6. doi: 10.1038/nature03712. Nature. 2005. PMID: 16001071 Free PMC article.
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury.
Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C, Penninger JM. Kuba K, et al. Among authors: penninger jm. Nat Med. 2005 Aug;11(8):875-9. doi: 10.1038/nm1267. Epub 2005 Jul 10. Nat Med. 2005. PMID: 16007097 Free PMC article.
Regulation of cancer cell migration and bone metastasis by RANKL.
Jones DH, Nakashima T, Sanchez OH, Kozieradzki I, Komarova SV, Sarosi I, Morony S, Rubin E, Sarao R, Hojilla CV, Komnenovic V, Kong YY, Schreiber M, Dixon SJ, Sims SM, Khokha R, Wada T, Penninger JM. Jones DH, et al. Among authors: penninger jm. Nature. 2006 Mar 30;440(7084):692-6. doi: 10.1038/nature04524. Nature. 2006. PMID: 16572175
632 results