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Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon C, Tucker C, Peng L, Lee CD, Lin TH, Yuan M, Cong Y, Wang L, Purser L, Williams JK, Pyo CW, Kosik I, Hu Z, Zhao M, Mohan D, Cooper AJR, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Drawbaugh D, Eaton B, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Holbrook MR, Nemazee D, Mascola JR, Wilson IA, Tan J. Dacon C, et al. Among authors: peng l. Science. 2022 Aug 12;377(6607):728-735. doi: 10.1126/science.abq3773. Epub 2022 Jul 12. Science. 2022. PMID: 35857439 Free PMC article.
Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model.
Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, Parren M, Peng L, Ricketts J, Ricciardi MJ, Rawlings SA, Smith DM, Nemazee D, Teijaro JR, Voss JE, Andrabi R, Briney B, Landais E, Sok D, Jardine JG, Burton DR. Rogers TF, et al. Among authors: peng l. bioRxiv [Preprint]. 2020 May 15:2020.05.11.088674. doi: 10.1101/2020.05.11.088674. bioRxiv. 2020. PMID: 32511387 Free PMC article. Updated. Preprint.
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.
Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, Parren M, Peng L, Ramirez S, Ricketts J, Ricciardi MJ, Rawlings SA, Wu NC, Yuan M, Smith DM, Nemazee D, Teijaro JR, Voss JE, Wilson IA, Andrabi R, Briney B, Landais E, Sok D, Jardine JG, Burton DR. Rogers TF, et al. Among authors: peng l. Science. 2020 Aug 21;369(6506):956-963. doi: 10.1126/science.abc7520. Epub 2020 Jun 15. Science. 2020. PMID: 32540903 Free PMC article.
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody.
Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, Deveau LM, Yockachonis TJ, Herbert AS, Battles MB, O'Brien CM, Brown ME, Geoghegan JC, Belk J, Peng L, Yang L, Hou Y, Scobey TD, Burton DR, Nemazee D, Dye JM, Voss JE, Gunn BM, McLellan JS, Baric RS, Gralinski LE, Walker LM. Rappazzo CG, et al. Among authors: peng l. Science. 2021 Feb 19;371(6531):823-829. doi: 10.1126/science.abf4830. Epub 2021 Jan 25. Science. 2021. PMID: 33495307 Free PMC article.
A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
Liu H, Yuan M, Huang D, Bangaru S, Lee CD, Peng L, Zhu X, Nemazee D, van Gils MJ, Sanders RW, Kornau HC, Reincke SM, Prüss H, Kreye J, Wu NC, Ward AB, Wilson IA. Liu H, et al. Among authors: peng l. bioRxiv [Preprint]. 2021 Feb 12:2021.02.11.430866. doi: 10.1101/2021.02.11.430866. bioRxiv. 2021. PMID: 33594361 Free PMC article. Updated. Preprint.
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants.
Yuan M, Huang D, Lee CD, Wu NC, Jackson AM, Zhu X, Liu H, Peng L, van Gils MJ, Sanders RW, Burton DR, Reincke SM, Prüss H, Kreye J, Nemazee D, Ward AB, Wilson IA. Yuan M, et al. Among authors: peng l. bioRxiv [Preprint]. 2021 Feb 17:2021.02.16.430500. doi: 10.1101/2021.02.16.430500. bioRxiv. 2021. PMID: 33619487 Free PMC article. Updated. Preprint.
Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants.
Cho H, Gonzales-Wartz KK, Huang D, Yuan M, Peterson M, Liang J, Beutler N, Torres JL, Cong Y, Postnikova E, Bangaru S, Talana CA, Shi W, Yang ES, Zhang Y, Leung K, Wang L, Peng L, Skinner J, Li S, Wu NC, Liu H, Dacon C, Moyer T, Cohen M, Zhao M, Lee FE, Weinberg RS, Douagi I, Gross R, Schmaljohn C, Pegu A, Mascola JR, Holbrook M, Nemazee D, Rogers TF, Ward AB, Wilson IA, Crompton PD, Tan J. Cho H, et al. Among authors: peng l. bioRxiv [Preprint]. 2021 Apr 1:2021.04.01.437942. doi: 10.1101/2021.04.01.437942. bioRxiv. 2021. PMID: 33821267 Free PMC article. Updated. Preprint.
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
Zhou P, Yuan M, Song G, Beutler N, Shaabani N, Huang D, He WT, Zhu X, Callaghan S, Yong P, Anzanello F, Peng L, Ricketts J, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Teijaro JR, Rogers TF, Wilson IA, Burton DR, Andrabi R. Zhou P, et al. Among authors: peng l. bioRxiv [Preprint]. 2022 Jan 21:2021.03.30.437769. doi: 10.1101/2021.03.30.437769. bioRxiv. 2022. PMID: 33821273 Free PMC article. Updated. Preprint.
9,346 results