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Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.
Alves CH, Sanz AS, Park B, Pellissier LP, Tanimoto N, Beck SC, Huber G, Murtaza M, Richard F, Sridevi Gurubaran I, Garcia Garrido M, Levelt CN, Rashbass P, Le Bivic A, Seeliger MW, Wijnholds J. Alves CH, et al. Among authors: pellissier lp. Hum Mol Genet. 2013 Jan 1;22(1):35-50. doi: 10.1093/hmg/dds398. Epub 2012 Sep 21. Hum Mol Genet. 2013. PMID: 23001562
CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice.
Pellissier LP, Lundvig DM, Tanimoto N, Klooster J, Vos RM, Richard F, Sothilingam V, Garcia Garrido M, Le Bivic A, Seeliger MW, Wijnholds J. Pellissier LP, et al. Hum Mol Genet. 2014 Jul 15;23(14):3759-71. doi: 10.1093/hmg/ddu089. Epub 2014 Feb 23. Hum Mol Genet. 2014. PMID: 24565864
Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.
Alves CH, Pellissier LP, Vos RM, Garcia Garrido M, Sothilingam V, Seide C, Beck SC, Klooster J, Furukawa T, Flannery JG, Verhaagen J, Seeliger MW, Wijnholds J. Alves CH, et al. Among authors: pellissier lp. Hum Mol Genet. 2014 Jul 1;23(13):3384-401. doi: 10.1093/hmg/ddu048. Epub 2014 Feb 2. Hum Mol Genet. 2014. PMID: 24493795
Specific tools for targeting and expression in Müller glial cells.
Pellissier LP, Hoek RM, Vos RM, Aartsen WM, Klimczak RR, Hoyng SA, Flannery JG, Wijnholds J. Pellissier LP, et al. Mol Ther Methods Clin Dev. 2014 Mar 19;1:14009. doi: 10.1038/mtm.2014.9. eCollection 2014. Mol Ther Methods Clin Dev. 2014. PMID: 26015954 Free PMC article.
33 results