Pellicciari R - Search Results

1

Progress and challenges of selective Farnesoid X Receptor modulation.

Massafra V, Pellicciari R, Gioiello A, van Mil SWC. Massafra V, et al. Among authors: pellicciari r. Pharmacol Ther. 2018 Nov;191:162-177. doi: 10.1016/j.pharmthera.2018.06.009. Epub 2018 Jun 20. Pharmacol Ther. 2018. PMID: 29933033 Free article. Review.

2

Semisynthetic bile acid FXR and TGR5 agonists: physicochemical properties, pharmacokinetics, and metabolism in the rat.

Roda A, Pellicciari R, Gioiello A, Neri F, Camborata C, Passeri D, De Franco F, Spinozzi S, Colliva C, Adorini L, Montagnani M, Aldini R. Roda A, et al. Among authors: pellicciari r. J Pharmacol Exp Ther. 2014 Jul;350(1):56-68. doi: 10.1124/jpet.114.214650. Epub 2014 May 1. J Pharmacol Exp Ther. 2014. PMID: 24784847

3

Bile acid derivatives as ligands of the farnesoid x receptor: molecular determinants for bile acid binding and receptor modulation.

Gioiello A, Cerra B, Mostarda S, Guercini C, Pellicciari R, Macchiarulo A. Gioiello A, et al. Among authors: pellicciari r. Curr Top Med Chem. 2014;14(19):2159-74. doi: 10.2174/1568026614666141112100208. Curr Top Med Chem. 2014. PMID: 25388535 Review.

4

Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow.

Marzano M, Fosso B, Colliva C, Notario E, Passeri D, Intranuovo M, Gioiello A, Adorini L, Pesole G, Pellicciari R, Moschetta A, Gadaleta RM. Marzano M, et al. Among authors: pellicciari r. Biomed Pharmacother. 2022 Sep;153:113380. doi: 10.1016/j.biopha.2022.113380. Epub 2022 Jul 19. Biomed Pharmacother. 2022. PMID: 36076475 Free article.

5

Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid.

Pellicciari R, Costantino G, Camaioni E, Sadeghpour BM, Entrena A, Willson TM, Fiorucci S, Clerici C, Gioiello A. Pellicciari R, et al. J Med Chem. 2004 Aug 26;47(18):4559-69. doi: 10.1021/jm049904b. J Med Chem. 2004. PMID: 15317466

6

Molecular dynamics simulation of the ligand binding domain of farnesoid X receptor. Insights into helix-12 stability and coactivator peptide stabilization in response to agonist binding.

Costantino G, Entrena-Guadix A, Macchiarulo A, Gioiello A, Pellicciari R. Costantino G, et al. Among authors: pellicciari r. J Med Chem. 2005 May 5;48(9):3251-9. doi: 10.1021/jm049182o. J Med Chem. 2005. PMID: 15857131

7

The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo.

Rizzo G, Disante M, Mencarelli A, Renga B, Gioiello A, Pellicciari R, Fiorucci S. Rizzo G, et al. Among authors: pellicciari r. Mol Pharmacol. 2006 Oct;70(4):1164-73. doi: 10.1124/mol.106.023820. Epub 2006 Jun 15. Mol Pharmacol. 2006. PMID: 16778009

8

Back door modulation of the farnesoid X receptor: design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives.

Pellicciari R, Gioiello A, Costantino G, Sadeghpour BM, Rizzo G, Meyer U, Parks DJ, Entrena-Guadix A, Fiorucci S. Pellicciari R, et al. J Med Chem. 2006 Jul 13;49(14):4208-15. doi: 10.1021/jm060294k. J Med Chem. 2006. PMID: 16821780

9

Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5.

Pellicciari R, Sato H, Gioiello A, Costantino G, Macchiarulo A, Sadeghpour BM, Giorgi G, Schoonjans K, Auwerx J. Pellicciari R, et al. J Med Chem. 2007 Sep 6;50(18):4265-8. doi: 10.1021/jm070633p. Epub 2007 Aug 9. J Med Chem. 2007. PMID: 17685603

10

Patented TGR5 modulators: a review (2006 - present).

Gioiello A, Rosatelli E, Nuti R, Macchiarulo A, Pellicciari R. Gioiello A, et al. Among authors: pellicciari r. Expert Opin Ther Pat. 2012 Dec;22(12):1399-414. doi: 10.1517/13543776.2012.733000. Epub 2012 Oct 6. Expert Opin Ther Pat. 2012. PMID: 23039746 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

275 results

Search Page