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Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer-associated fibroblasts.
Cirillo F, Pellegrino M, Talia M, Perrotta ID, Rigiracciolo DC, Spinelli A, Scordamaglia D, Muglia L, Guzzi R, Miglietta AM, De Francesco EM, Belfiore A, Maggiolini M, Lappano R. Cirillo F, et al. Among authors: pellegrino m. Clin Transl Med. 2021 Nov;11(11):e516. doi: 10.1002/ctm2.516. Clin Transl Med. 2021. PMID: 34841688 Free PMC article.
GPER mediates activation of HIF1α/VEGF signaling by estrogens.
De Francesco EM, Pellegrino M, Santolla MF, Lappano R, Ricchio E, Abonante S, Maggiolini M. De Francesco EM, et al. Among authors: pellegrino m. Cancer Res. 2014 Aug 1;74(15):4053-64. doi: 10.1158/0008-5472.CAN-13-3590. Epub 2014 Jun 3. Cancer Res. 2014. PMID: 24894716
SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer.
Santolla MF, Avino S, Pellegrino M, De Francesco EM, De Marco P, Lappano R, Vivacqua A, Cirillo F, Rigiracciolo DC, Scarpelli A, Abonante S, Maggiolini M. Santolla MF, et al. Among authors: pellegrino m. Cell Death Dis. 2015 Jul 30;6(7):e1834. doi: 10.1038/cddis.2015.201. Cell Death Dis. 2015. PMID: 26225773 Free PMC article.
Ligand activated progesterone receptor B drives autophagy-senescence transition through a Beclin-1/Bcl-2 dependent mechanism in human breast cancer cells.
De Amicis F, Guido C, Santoro M, Giordano F, Donà A, Rizza P, Pellegrino M, Perrotta I, Bonofiglio D, Sisci D, Panno ML, Tramontano D, Aquila S, Andò S. De Amicis F, et al. Among authors: pellegrino m. Oncotarget. 2016 Sep 6;7(36):57955-57969. doi: 10.18632/oncotarget.10799. Oncotarget. 2016. PMID: 27462784 Free PMC article.
794 results