Pellecchia M - Search Results

1

Perspectives on NMR in drug discovery: a technique comes of age.

Pellecchia M, Bertini I, Cowburn D, Dalvit C, Giralt E, Jahnke W, James TL, Homans SW, Kessler H, Luchinat C, Meyer B, Oschkinat H, Peng J, Schwalbe H, Siegal G. Pellecchia M, et al. Nat Rev Drug Discov. 2008 Sep;7(9):738-45. doi: 10.1038/nrd2606. Nat Rev Drug Discov. 2008. PMID: 19172689 Free PMC article. Review.

2

NMR in the acceleration of drug discovery.

Sem DS, Pellecchia M. Sem DS, et al. Among authors: pellecchia m. Curr Opin Drug Discov Devel. 2001 Jul;4(4):479-92. Curr Opin Drug Discov Devel. 2001. PMID: 11727313 Review.

3

NMR-based structural characterization of large protein-ligand interactions.

Pellecchia M, Meininger D, Dong Q, Chang E, Jack R, Sem DS. Pellecchia M, et al. J Biomol NMR. 2002 Feb;22(2):165-73. doi: 10.1023/a:1014256707875. J Biomol NMR. 2002. PMID: 11883777

4

NMR in drug discovery.

Pellecchia M, Sem DS, Wüthrich K. Pellecchia M, et al. Nat Rev Drug Discov. 2002 Mar;1(3):211-9. doi: 10.1038/nrd748. Nat Rev Drug Discov. 2002. PMID: 12120505 Review.

5

NMR-based techniques in the hit identification and optimisation processes.

Pellecchia M, Becattini B, Crowell KJ, Fattorusso R, Forino M, Fragai M, Jung D, Mustelin T, Tautz L. Pellecchia M, et al. Expert Opin Ther Targets. 2004 Dec;8(6):597-611. doi: 10.1517/14728222.8.6.597. Expert Opin Ther Targets. 2004. PMID: 15584865 Review.

6

Solution nuclear magnetic resonance spectroscopy techniques for probing intermolecular interactions.

Pellecchia M. Pellecchia M. Chem Biol. 2005 Sep;12(9):961-71. doi: 10.1016/j.chembiol.2005.08.013. Chem Biol. 2005. PMID: 16183020 Review.

7

The Nuclear Overhauser Effect in the lead identification process.

Leone M, Freeze HH, Chan CS, Pellecchia M. Leone M, et al. Among authors: pellecchia m. Curr Drug Discov Technol. 2006 Jun;3(2):91-100. doi: 10.2174/157016306778108884. Curr Drug Discov Technol. 2006. PMID: 16925517 Review.

8

HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery.

Wu B, Zhang Z, Noberini R, Barile E, Giulianotti M, Pinilla C, Houghten RA, Pasquale EB, Pellecchia M. Wu B, et al. Among authors: pellecchia m. Chem Biol. 2013 Jan 24;20(1):19-33. doi: 10.1016/j.chembiol.2012.10.015. Chem Biol. 2013. PMID: 23352136 Free PMC article.

9

NMR-based approaches for the identification and optimization of inhibitors of protein-protein interactions.

Barile E, Pellecchia M. Barile E, et al. Among authors: pellecchia m. Chem Rev. 2014 May 14;114(9):4749-63. doi: 10.1021/cr500043b. Epub 2014 Apr 8. Chem Rev. 2014. PMID: 24712885 Free PMC article. Review. No abstract available.

10

HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

Baggio C, Cerofolini L, Fragai M, Luchinat C, Pellecchia M. Baggio C, et al. Among authors: pellecchia m. ACS Med Chem Lett. 2018 Jan 17;9(2):137-142. doi: 10.1021/acsmedchemlett.7b00483. eCollection 2018 Feb 8. ACS Med Chem Lett. 2018. PMID: 29456802 Free PMC article.

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