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412 results

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Page 1
Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54.
Coecke S, Ahr H, Blaauboer BJ, Bremer S, Casati S, Castell J, Combes R, Corvi R, Crespi CL, Cunningham ML, Elaut G, Eletti B, Freidig A, Gennari A, Ghersi-Egea JF, Guillouzo A, Hartung T, Hoet P, Ingelman-Sundberg M, Munn S, Janssens W, Ladstetter B, Leahy D, Long A, Meneguz A, Monshouwer M, Morath S, Nagelkerke F, Pelkonen O, Ponti J, Prieto P, Richert L, Sabbioni E, Schaack B, Steiling W, Testai E, Vericat JA, Worth A. Coecke S, et al. Among authors: pelkonen o. Altern Lab Anim. 2006 Feb;34(1):49-84. doi: 10.1177/026119290603400113. Altern Lab Anim. 2006. PMID: 16522150 No abstract available.
Toxicokinetics and metabolism.
Coecke S, Blaauboer BJ, Elaut G, Freeman S, Freidig A, Gensmantel N, Hoet P, Kapoulas VM, Ladstetter B, Langley G, Leahy D, Mannens G, Meneguz A, Monshouwer M, Nemery B, Pelkonen O, Pfaller W, Prieto P, Proctor N, Rogiers V, Rostami-Hodjegan A, Sabbioni E, Steiling W, van de Sandt JJ. Coecke S, et al. Among authors: pelkonen o. Altern Lab Anim. 2005 Jul;33 Suppl 1:147-75. doi: 10.1177/026119290503301s15. Altern Lab Anim. 2005. PMID: 16194147 No abstract available.
Reproductive and developmental toxicity.
Bremer S, Cortvrindt R, Daston G, Eletti B, Mantovani A, Maranghi F, Pelkonen O, Ruhdel I, Spielmann H. Bremer S, et al. Among authors: pelkonen o. Altern Lab Anim. 2005 Jul;33 Suppl 1:183-209. doi: 10.1177/026119290503301s17. Altern Lab Anim. 2005. PMID: 16194149 No abstract available.
Establishing a systematic framework to characterise in vitro methods for human hepatic metabolic clearance.
Gouliarmou V, Lostia AM, Coecke S, Bernasconi C, Bessems J, Dorne JL, Ferguson S, Testai E, Remy UG, Brian Houston J, Monshouwer M, Nong A, Pelkonen O, Morath S, Wetmore BA, Worth A, Zanelli U, Zorzoli MC, Whelan M. Gouliarmou V, et al. Among authors: pelkonen o. Toxicol In Vitro. 2018 Dec;53:233-244. doi: 10.1016/j.tiv.2018.08.004. Epub 2018 Aug 9. Toxicol In Vitro. 2018. PMID: 30099088 Free PMC article.
Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study.
Bernasconi C, Pelkonen O, Andersson TB, Strickland J, Wilk-Zasadna I, Asturiol D, Cole T, Liska R, Worth A, Müller-Vieira U, Richert L, Chesne C, Coecke S. Bernasconi C, et al. Among authors: pelkonen o. Toxicol In Vitro. 2019 Oct;60:212-228. doi: 10.1016/j.tiv.2019.05.019. Epub 2019 May 31. Toxicol In Vitro. 2019. PMID: 31158489 Free PMC article.
Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.
Adler S, Basketter D, Creton S, Pelkonen O, van Benthem J, Zuang V, Andersen KE, Angers-Loustau A, Aptula A, Bal-Price A, Benfenati E, Bernauer U, Bessems J, Bois FY, Boobis A, Brandon E, Bremer S, Broschard T, Casati S, Coecke S, Corvi R, Cronin M, Daston G, Dekant W, Felter S, Grignard E, Gundert-Remy U, Heinonen T, Kimber I, Kleinjans J, Komulainen H, Kreiling R, Kreysa J, Leite SB, Loizou G, Maxwell G, Mazzatorta P, Munn S, Pfuhler S, Phrakonkham P, Piersma A, Poth A, Prieto P, Repetto G, Rogiers V, Schoeters G, Schwarz M, Serafimova R, Tähti H, Testai E, van Delft J, van Loveren H, Vinken M, Worth A, Zaldivar JM. Adler S, et al. Among authors: pelkonen o. Arch Toxicol. 2011 May;85(5):367-485. doi: 10.1007/s00204-011-0693-2. Epub 2011 May 1. Arch Toxicol. 2011. PMID: 21533817 Review.
Cytochrome P450 Induction and Xeno-Sensing Receptors Pregnane X Receptor, Constitutive Androstane Receptor, Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor α at the Crossroads of Toxicokinetics and Toxicodynamics.
Hakkola J, Bernasconi C, Coecke S, Richert L, Andersson TB, Pelkonen O. Hakkola J, et al. Among authors: pelkonen o. Basic Clin Pharmacol Toxicol. 2018 Sep;123 Suppl 5:42-50. doi: 10.1111/bcpt.13004. Epub 2018 Apr 29. Basic Clin Pharmacol Toxicol. 2018. PMID: 29527807 Free article. Review.
412 results