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JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia.
Aranda-Tavío H, Recio C, Martín-Acosta P, Guerra-Rodríguez M, Brito-Casillas Y, Blanco R, Junco V, León J, Montero JC, Gandullo-Sánchez L, McNaughton-Smith G, Zapata JM, Pandiella A, Amesty A, Estévez-Braun A, Fernández-Pérez L, Guerra B. Aranda-Tavío H, et al. Among authors: martin acosta p. Biomed Pharmacother. 2021 Dec;144:112330. doi: 10.1016/j.biopha.2021.112330. Epub 2021 Oct 19. Biomed Pharmacother. 2021. PMID: 34673425 Free article.
Mechanistic insights into the activation of ester prodrugs of 666-15.
Xie F, Martín-Acosta P, Li BX, Xiao X. Xie F, et al. Among authors: martin acosta p. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127455. doi: 10.1016/j.bmcl.2020.127455. Epub 2020 Jul 28. Bioorg Med Chem Lett. 2020. PMID: 32730943 Free PMC article.
Kinetically guided radical-based synthesis of C(sp3)-C(sp3) linkages on DNA.
Wang J, Lundberg H, Asai S, Martín-Acosta P, Chen JS, Brown S, Farrell W, Dushin RG, O'Donnell CJ, Ratnayake AS, Richardson P, Liu Z, Qin T, Blackmond DG, Baran PS. Wang J, et al. Among authors: martin acosta p. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6404-E6410. doi: 10.1073/pnas.1806900115. Epub 2018 Jun 26. Proc Natl Acad Sci U S A. 2018. PMID: 29946037 Free PMC article.
12 results