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The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer.
Yan S, Xuan J, Brajanovski N, Tancock MRC, Madhamshettiwar PB, Simpson KJ, Ellis S, Kang J, Cullinane C, Sheppard KE, Hannan KM, Hannan RD, Sanij E, Pearson RB, Chan KT. Yan S, et al. Among authors: pearson rb. Br J Cancer. 2021 Feb;124(3):616-627. doi: 10.1038/s41416-020-01158-z. Epub 2020 Nov 11. Br J Cancer. 2021. PMID: 33173151 Free PMC article.
Protein kinase-dependent phosphorylation of the Menkes copper P-type ATPase.
Voskoboinik I, Fernando R, Veldhuis N, Hannan KM, Marmy-Conus N, Pearson RB, Camakaris J. Voskoboinik I, et al. Among authors: pearson rb. Biochem Biophys Res Commun. 2003 Mar 28;303(1):337-42. doi: 10.1016/s0006-291x(03)00329-2. Biochem Biophys Res Commun. 2003. PMID: 12646208
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.
Hannan KM, Brandenburger Y, Jenkins A, Sharkey K, Cavanaugh A, Rothblum L, Moss T, Poortinga G, McArthur GA, Pearson RB, Hannan RD. Hannan KM, et al. Among authors: pearson rb. Mol Cell Biol. 2003 Dec;23(23):8862-77. doi: 10.1128/MCB.23.23.8862-8877.2003. Mol Cell Biol. 2003. PMID: 14612424 Free PMC article.
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation.
Poortinga G, Hannan KM, Snelling H, Walkley CR, Jenkins A, Sharkey K, Wall M, Brandenburger Y, Palatsides M, Pearson RB, McArthur GA, Hannan RD. Poortinga G, et al. Among authors: pearson rb. EMBO J. 2004 Aug 18;23(16):3325-35. doi: 10.1038/sj.emboj.7600335. Epub 2004 Jul 29. EMBO J. 2004. PMID: 15282543 Free PMC article.
Mutation of the PIK3CA gene in ovarian and breast cancer.
Campbell IG, Russell SE, Choong DY, Montgomery KG, Ciavarella ML, Hooi CS, Cristiano BE, Pearson RB, Phillips WA. Campbell IG, et al. Among authors: pearson rb. Cancer Res. 2004 Nov 1;64(21):7678-81. doi: 10.1158/0008-5472.CAN-04-2933. Cancer Res. 2004. PMID: 15520168
155 results