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Page 1
Leptin Signaling Suppression in Macrophages Improves Immunometabolic Outcomes in Obesity.
Monteiro LB, Prodonoff JS, Favero de Aguiar C, Correa-da-Silva F, Castoldi A, Bakker NVT, Davanzo GG, Castelucci B, Pereira JADS, Curtis J, Büscher J, Reis LMD, Castro G, Ribeiro G, Virgílio-da-Silva JV, Adamoski D, Dias SMG, Consonni SR, Donato J, Pearce EJ, Câmara NOS, Moraes-Vieira PM. Monteiro LB, et al. Among authors: pearce ej. Diabetes. 2022 Jul 1;71(7):1546-1561. doi: 10.2337/db21-0842. Diabetes. 2022. PMID: 35377454
Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2.
Sanin DE, Matsushita M, Klein Geltink RI, Grzes KM, van Teijlingen Bakker N, Corrado M, Kabat AM, Buck MD, Qiu J, Lawless SJ, Cameron AM, Villa M, Baixauli F, Patterson AE, Hässler F, Curtis JD, O'Neill CM, O'Sullivan D, Wu D, Mittler G, Huang SC, Pearce EL, Pearce EJ. Sanin DE, et al. Among authors: pearce ej, pearce el. Immunity. 2018 Dec 18;49(6):1021-1033.e6. doi: 10.1016/j.immuni.2018.10.011. Immunity. 2018. PMID: 30566880 Free PMC article.
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.
Puleston DJ, Buck MD, Klein Geltink RI, Kyle RL, Caputa G, O'Sullivan D, Cameron AM, Castoldi A, Musa Y, Kabat AM, Zhang Y, Flachsmann LJ, Field CS, Patterson AE, Scherer S, Alfei F, Baixauli F, Austin SK, Kelly B, Matsushita M, Curtis JD, Grzes KM, Villa M, Corrado M, Sanin DE, Qiu J, Pällman N, Paz K, Maccari ME, Blazar BR, Mittler G, Buescher JM, Zehn D, Rospert S, Pearce EJ, Balabanov S, Pearce EL. Puleston DJ, et al. Among authors: pearce ej, pearce el. Cell Metab. 2019 Aug 6;30(2):352-363.e8. doi: 10.1016/j.cmet.2019.05.003. Epub 2019 May 23. Cell Metab. 2019. PMID: 31130465 Free PMC article.
Metabolic adaptations of tissue-resident immune cells.
Caputa G, Castoldi A, Pearce EJ. Caputa G, et al. Among authors: pearce ej. Nat Immunol. 2019 Jul;20(7):793-801. doi: 10.1038/s41590-019-0407-0. Epub 2019 Jun 18. Nat Immunol. 2019. PMID: 31213715 Review.
Triacylglycerol synthesis enhances macrophage inflammatory function.
Castoldi A, Monteiro LB, van Teijlingen Bakker N, Sanin DE, Rana N, Corrado M, Cameron AM, Hässler F, Matsushita M, Caputa G, Klein Geltink RI, Büscher J, Edwards-Hicks J, Pearce EL, Pearce EJ. Castoldi A, et al. Among authors: pearce ej, pearce el. Nat Commun. 2020 Aug 14;11(1):4107. doi: 10.1038/s41467-020-17881-3. Nat Commun. 2020. PMID: 32796836 Free PMC article.
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver.
Remmerie A, Martens L, Thoné T, Castoldi A, Seurinck R, Pavie B, Roels J, Vanneste B, De Prijck S, Vanhockerhout M, Binte Abdul Latib M, Devisscher L, Hoorens A, Bonnardel J, Vandamme N, Kremer A, Borghgraef P, Van Vlierberghe H, Lippens S, Pearce E, Saeys Y, Scott CL. Remmerie A, et al. Immunity. 2020 Sep 15;53(3):641-657.e14. doi: 10.1016/j.immuni.2020.08.004. Epub 2020 Sep 3. Immunity. 2020. PMID: 32888418 Free PMC article.
Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease.
Erny D, Dokalis N, Mezö C, Castoldi A, Mossad O, Staszewski O, Frosch M, Villa M, Fuchs V, Mayer A, Neuber J, Sosat J, Tholen S, Schilling O, Vlachos A, Blank T, Gomez de Agüero M, Macpherson AJ, Pearce EJ, Prinz M. Erny D, et al. Among authors: pearce ej. Cell Metab. 2021 Nov 2;33(11):2260-2276.e7. doi: 10.1016/j.cmet.2021.10.010. Cell Metab. 2021. PMID: 34731656 Free article.
A common framework of monocyte-derived macrophage activation.
Sanin DE, Ge Y, Marinkovic E, Kabat AM, Castoldi A, Caputa G, Grzes KM, Curtis JD, Thompson EA, Willenborg S, Dichtl S, Reinhardt S, Dahl A, Pearce EL, Eming SA, Gerbaulet A, Roers A, Murray PJ, Pearce EJ. Sanin DE, et al. Among authors: pearce ej, pearce el. Sci Immunol. 2022 Apr 15;7(70):eabl7482. doi: 10.1126/sciimmunol.abl7482. Epub 2022 Apr 15. Sci Immunol. 2022. PMID: 35427180
Intracellular infection and immune system cues rewire adipocytes to acquire immune function.
Caputa G, Matsushita M, Sanin DE, Kabat AM, Edwards-Hicks J, Grzes KM, Pohlmeyer R, Stanczak MA, Castoldi A, Cupovic J, Forde AJ, Apostolova P, Seidl M, van Teijlingen Bakker N, Villa M, Baixauli F, Quintana A, Hackl A, Flachsmann L, Hässler F, Curtis JD, Patterson AE, Henneke P, Pearce EL, Pearce EJ. Caputa G, et al. Among authors: pearce ej, pearce el. Cell Metab. 2022 May 3;34(5):747-760.e6. doi: 10.1016/j.cmet.2022.04.008. Cell Metab. 2022. PMID: 35508110 Free article.
255 results