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Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling.
Moreno E, Andradas C, Medrano M, Caffarel MM, Pérez-Gómez E, Blasco-Benito S, Gómez-Cañas M, Pazos MR, Irving AJ, Lluís C, Canela EI, Fernández-Ruiz J, Guzmán M, McCormick PJ, Sánchez C. Moreno E, et al. Among authors: pazos mr. J Biol Chem. 2014 Aug 8;289(32):21960-72. doi: 10.1074/jbc.M114.561761. Epub 2014 Jun 18. J Biol Chem. 2014. PMID: 24942731 Free PMC article.
New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking.
Ragusa G, Gómez-Cañas M, Morales P, Rodríguez-Cueto C, Pazos MR, Asproni B, Cichero E, Fossa P, Pinna GA, Jagerovic N, Fernández-Ruiz J, Murineddu G. Ragusa G, et al. Among authors: pazos mr. Eur J Med Chem. 2017 Feb 15;127:398-412. doi: 10.1016/j.ejmech.2017.01.002. Epub 2017 Jan 4. Eur J Med Chem. 2017. PMID: 28088085
Role of CB2 receptors in neuroprotective effects of cannabinoids.
Fernández-Ruiz J, Pazos MR, García-Arencibia M, Sagredo O, Ramos JA. Fernández-Ruiz J, et al. Among authors: pazos mr. Mol Cell Endocrinol. 2008 Apr 16;286(1-2 Suppl 1):S91-6. doi: 10.1016/j.mce.2008.01.001. Epub 2008 Jan 17. Mol Cell Endocrinol. 2008. PMID: 18291574 Review.
The endocannabinoid system in Huntington's disease.
Pazos MR, Sagredo O, Fernández-Ruiz J. Pazos MR, et al. Curr Pharm Des. 2008;14(23):2317-25. doi: 10.2174/138161208785740108. Curr Pharm Des. 2008. PMID: 18781982 Review.
The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways.
del Río C, Navarrete C, Collado JA, Bellido ML, Gómez-Cañas M, Pazos MR, Fernández-Ruiz J, Pollastro F, Appendino G, Calzado MA, Cantarero I, Muñoz E. del Río C, et al. Among authors: pazos mr. Sci Rep. 2016 Feb 18;6:21703. doi: 10.1038/srep21703. Sci Rep. 2016. PMID: 26887982 Free PMC article.
Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties.
Deiana V, Gómez-Cañas M, Pazos MR, Fernández-Ruiz J, Asproni B, Cichero E, Fossa P, Muñoz E, Deligia F, Murineddu G, García-Arencibia M, Pinna GA. Deiana V, et al. Among authors: pazos mr. Eur J Med Chem. 2016 Apr 13;112:66-80. doi: 10.1016/j.ejmech.2016.02.005. Epub 2016 Feb 6. Eur J Med Chem. 2016. PMID: 26890113
45 results