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Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators.
Kline GM, Paxman RJ, Lin CY, Madrazo N, Yoon L, Grandjean JMD, Lee K, Nugroho K, Powers ET, Wiseman RL, Kelly JW. Kline GM, et al. Among authors: paxman rj. ACS Chem Biol. 2023 Aug 18;18(8):1719-1729. doi: 10.1021/acschembio.3c00042. Epub 2023 Jul 31. ACS Chem Biol. 2023. PMID: 37523656 Free PMC article.
Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming.
Grandjean JMD, Madhavan A, Cech L, Seguinot BO, Paxman RJ, Smith E, Scampavia L, Powers ET, Cooley CB, Plate L, Spicer TP, Kelly JW, Wiseman RL. Grandjean JMD, et al. Among authors: paxman rj. Nat Chem Biol. 2020 Oct;16(10):1052-1061. doi: 10.1038/s41589-020-0584-z. Epub 2020 Jul 20. Nat Chem Biol. 2020. PMID: 32690944 Free PMC article.
32 results