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Reversible rearrangement of the cellular cytoskeleton: A key to the broad-spectrum antiviral activity of novel amphiphilic polymers.
Dabrowska A, Botwina P, Barreto-Duran E, Kubisiak A, Obloza M, Synowiec A, Szczepanski A, Targosz-Korecka M, Szczubialka K, Nowakowska M, Pyrc K. Dabrowska A, et al. Among authors: botwina p. Mater Today Bio. 2023 Aug 7;22:100763. doi: 10.1016/j.mtbio.2023.100763. eCollection 2023 Oct. Mater Today Bio. 2023. PMID: 37600352 Free PMC article.
Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses.
Napolitano V, Dabrowska A, Schorpp K, Mourão A, Barreto-Duran E, Benedyk M, Botwina P, Brandner S, Bostock M, Chykunova Y, Czarna A, Dubin G, Fröhlich T, Hölscher M, Jedrysik M, Matsuda A, Owczarek K, Pachota M, Plettenburg O, Potempa J, Rothenaigner I, Schlauderer F, Slysz K, Szczepanski A, Greve-Isdahl Mohn K, Blomberg B, Sattler M, Hadian K, Popowicz GM, Pyrc K. Napolitano V, et al. Among authors: botwina p. Cell Chem Biol. 2022 May 19;29(5):774-784.e8. doi: 10.1016/j.chembiol.2021.11.006. Epub 2022 Jan 11. Cell Chem Biol. 2022. PMID: 35021060 Free PMC article.
l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells.
Sancineto L, Ostacolo C, Ortega-Alarcon D, Jimenez-Alesanco A, Ceballos-Laita L, Vega S, Abian O, Velazquez-Campoy A, Moretti S, Dabrowska A, Botwina P, Synowiec A, Kula-Pacurar A, Pyrc K, Iraci N, Santi C. Sancineto L, et al. Among authors: botwina p. Molecules. 2021 Oct 7;26(19):6062. doi: 10.3390/molecules26196062. Molecules. 2021. PMID: 34641606 Free PMC article.
Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of Mpro and Its Antiviral Activity in Cells against SARS-CoV-2.
Mangiavacchi F, Botwina P, Menichetti E, Bagnoli L, Rosati O, Marini F, Fonseca SF, Abenante L, Alves D, Dabrowska A, Kula-Pacurar A, Ortega-Alarcon D, Jimenez-Alesanco A, Ceballos-Laita L, Vega S, Rizzuti B, Abian O, Lenardão EJ, Velazquez-Campoy A, Pyrc K, Sancineto L, Santi C. Mangiavacchi F, et al. Among authors: botwina p. Int J Mol Sci. 2021 Jun 30;22(13):7048. doi: 10.3390/ijms22137048. Int J Mol Sci. 2021. PMID: 34208928 Free PMC article.
HTCC as a Polymeric Inhibitor of SARS-CoV-2 and MERS-CoV.
Milewska A, Chi Y, Szczepanski A, Barreto-Duran E, Dabrowska A, Botwina P, Obloza M, Liu K, Liu D, Guo X, Ge Y, Li J, Cui L, Ochman M, Urlik M, Rodziewicz-Motowidlo S, Zhu F, Szczubialka K, Nowakowska M, Pyrc K. Milewska A, et al. Among authors: botwina p. J Virol. 2021 Jan 28;95(4):e01622-20. doi: 10.1128/JVI.01622-20. Print 2021 Jan 28. J Virol. 2021. PMID: 33219167 Free PMC article.
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