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TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.
Liu G, Haw TJ, Starkey MR, Philp AM, Pavlidis S, Nalkurthi C, Nair PM, Gomez HM, Hanish I, Hsu AC, Hortle E, Pickles S, Rojas-Quintero J, Estepar RSJ, Marshall JE, Kim RY, Collison AM, Mattes J, Idrees S, Faiz A, Hansbro NG, Fukui R, Murakami Y, Cheng HS, Tan NS, Chotirmall SH, Horvat JC, Foster PS, Oliver BG, Polverino F, Ieni A, Monaco F, Caramori G, Sohal SS, Bracke KR, Wark PA, Adcock IM, Miyake K, Sin DD, Hansbro PM. Liu G, et al. Among authors: pavlidis s. Nat Commun. 2023 Nov 14;14(1):7349. doi: 10.1038/s41467-023-42913-z. Nat Commun. 2023. PMID: 37963864 Free PMC article.
A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease.
Haw TJ, Starkey MR, Nair PM, Pavlidis S, Liu G, Nguyen DH, Hsu AC, Hanish I, Kim RY, Collison AM, Inman MD, Wark PA, Foster PS, Knight DA, Mattes J, Yagita H, Adcock IM, Horvat JC, Hansbro PM. Haw TJ, et al. Among authors: pavlidis s. Mucosal Immunol. 2016 Jul;9(4):859-72. doi: 10.1038/mi.2015.111. Epub 2015 Nov 11. Mucosal Immunol. 2016. PMID: 26555706 Free article.
Toll-like receptor 2 and 4 have opposing roles in the pathogenesis of cigarette smoke-induced chronic obstructive pulmonary disease.
Haw TJ, Starkey MR, Pavlidis S, Fricker M, Arthurs AL, Nair PM, Liu G, Hanish I, Kim RY, Foster PS, Horvat JC, Adcock IM, Hansbro PM. Haw TJ, et al. Among authors: pavlidis s. Am J Physiol Lung Cell Mol Physiol. 2018 Feb 1;314(2):L298-L317. doi: 10.1152/ajplung.00154.2017. Epub 2017 Oct 12. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29025711 Free PMC article.
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis.
Starkey MR, Plank MW, Casolari P, Papi A, Pavlidis S, Guo Y, Cameron GJM, Haw TJ, Tam A, Obiedat M, Donovan C, Hansbro NG, Nguyen DH, Nair PM, Kim RY, Horvat JC, Kaiko GE, Durum SK, Wark PA, Sin DD, Caramori G, Adcock IM, Foster PS, Hansbro PM. Starkey MR, et al. Among authors: pavlidis s. Eur Respir J. 2019 Jul 18;54(1):1800174. doi: 10.1183/13993003.00174-2018. Print 2019 Jul. Eur Respir J. 2019. PMID: 31196943 Free PMC article.
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma.
Ali MK, Kim RY, Brown AC, Mayall JR, Karim R, Pinkerton JW, Liu G, Martin KL, Starkey MR, Pillar AL, Donovan C, Pathinayake PS, Carroll OR, Trinder D, Tay HL, Badi YE, Kermani NZ, Guo YK, Aryal R, Mumby S, Pavlidis S, Adcock IM, Weaver J, Xenaki D, Oliver BG, Holliday EG, Foster PS, Wark PA, Johnstone DM, Milward EA, Hansbro PM, Horvat JC. Ali MK, et al. Among authors: pavlidis s. Eur Respir J. 2020 Apr 23;55(4):1901340. doi: 10.1183/13993003.01340-2019. Print 2020 Apr. Eur Respir J. 2020. PMID: 32184317 Free article.
Corticosteroid modulation of immunoglobulin expression and B-cell function in COPD.
Lee J, Machin M, Russell KE, Pavlidis S, Zhu J, Barnes PJ, Chung KF, Adcock IM, Durham AL. Lee J, et al. Among authors: pavlidis s. FASEB J. 2016 May;30(5):2014-26. doi: 10.1096/fj.201500135. Epub 2016 Feb 17. FASEB J. 2016. PMID: 26887440 Free article.
FP may reduce the adaptive immune response in COPD and may be more effective in patients with an increased B-cell/antibody response indicated by high autoantibody titers.-Lee, J., Machin, M., Russell, K. E., Pavlidis, S., Zhu, J., Barnes, P. J., Chung, K. F., Adcock …
FP may reduce the adaptive immune response in COPD and may be more effective in patients with an increased B-cell/antibody response indicate …
Macrophage migration inhibitory factor promotes glucocorticoid resistance of neutrophilic inflammation in a murine model of severe asthma.
Allam VSRR, Pavlidis S, Liu G, Kermani NZ, Simpson J, To J, Donnelly S, Guo YK, Hansbro PM, Phipps S, Morand EF, Djukanovic R, Sterk P, Chung KF, Adcock I, Harris J, Sukkar MB. Allam VSRR, et al. Among authors: pavlidis s. Thorax. 2023 Jul;78(7):661-673. doi: 10.1136/thorax-2021-218555. Epub 2022 Nov 7. Thorax. 2023. PMID: 36344253
52 results