Pavek P - Search Results

1

Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS).

Kubackova J, Holas O, Zbytovska J, Vranikova B, Zeng G, Pavek P, Mullertz A. Kubackova J, et al. Among authors: pavek p. Pharmaceutics. 2021 Mar 28;13(4):459. doi: 10.3390/pharmaceutics13040459. Pharmaceutics. 2021. PMID: 33800701 Free PMC article.

2

Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation.

Dusek J, Carazo A, Trejtnar F, Hyrsova L, Holas O, Smutny T, Micuda S, Pavek P. Dusek J, et al. Among authors: pavek p. Food Chem Toxicol. 2017 Nov;109(Pt 1):130-142. doi: 10.1016/j.fct.2017.09.007. Epub 2017 Sep 5. Food Chem Toxicol. 2017. PMID: 28887089

3

Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling.

Carazo A, Dusek J, Holas O, Skoda J, Hyrsova L, Smutny T, Soukup T, Dosedel M, Pávek P. Carazo A, et al. Among authors: pavek p. Front Pharmacol. 2018 Oct 11;9:993. doi: 10.3389/fphar.2018.00993. eCollection 2018. Front Pharmacol. 2018. PMID: 30364229 Free PMC article.

4

Stilbene compound trans-3,4,5,4´-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver.

Dusek J, Skoda J, Holas O, Horvatova A, Smutny T, Linhartova L, Hirsova P, Kucera O, Micuda S, Braeuning A, Pavek P. Dusek J, et al. Among authors: pavek p. Toxicol Lett. 2019 Oct 1;313:1-10. doi: 10.1016/j.toxlet.2019.05.024. Epub 2019 Jun 4. Toxicol Lett. 2019. PMID: 31170421

5

3β-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3α-epimer by hepatic metabolism.

Stefela A, Kaspar M, Drastik M, Holas O, Hroch M, Smutny T, Skoda J, Hutníková M, Pandey AV, Micuda S, Kudova E, Pavek P. Stefela A, et al. Among authors: pavek p. J Steroid Biochem Mol Biol. 2020 Sep;202:105702. doi: 10.1016/j.jsbmb.2020.105702. Epub 2020 Jun 4. J Steroid Biochem Mol Biol. 2020. PMID: 32505574

6

Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network.

Vinarov Z, Abrahamsson B, Artursson P, Batchelor H, Berben P, Bernkop-Schnürch A, Butler J, Ceulemans J, Davies N, Dupont D, Flaten GE, Fotaki N, Griffin BT, Jannin V, Keemink J, Kesisoglou F, Koziolek M, Kuentz M, Mackie A, Meléndez-Martínez AJ, McAllister M, Müllertz A, O'Driscoll CM, Parrott N, Paszkowska J, Pavek P, Porter CJH, Reppas C, Stillhart C, Sugano K, Toader E, Valentová K, Vertzoni M, De Wildt SN, Wilson CG, Augustijns P. Vinarov Z, et al. Among authors: pavek p. Adv Drug Deliv Rev. 2021 Apr;171:289-331. doi: 10.1016/j.addr.2021.02.001. Epub 2021 Feb 18. Adv Drug Deliv Rev. 2021. PMID: 33610694 Free article. Review.

7

PLGA Based Nanospheres as a Potent Macrophage-Specific Drug Delivery System.

Boltnarova B, Kubackova J, Skoda J, Stefela A, Smekalova M, Svacinova P, Pavkova I, Dittrich M, Scherman D, Zbytovska J, Pavek P, Holas O. Boltnarova B, et al. Among authors: pavek p. Nanomaterials (Basel). 2021 Mar 16;11(3):749. doi: 10.3390/nano11030749. Nanomaterials (Basel). 2021. PMID: 33809764 Free PMC article.

8

Fully automatic flow-based device for monitoring of drug permeation across a cell monolayer.

Zelená L, Marques SS, Segundo MA, Miró M, Pávek P, Sklenářová H, Solich P. Zelená L, et al. Among authors: pavek p. Anal Bioanal Chem. 2016 Jan;408(3):971-81. doi: 10.1007/s00216-015-9194-0. Epub 2015 Nov 28. Anal Bioanal Chem. 2016. PMID: 26615589

9

Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation.

Hyrsova L, Smutny T, Trejtnar F, Pavek P. Hyrsova L, et al. Among authors: pavek p. Drug Metab Rev. 2016 May;48(2):139-58. doi: 10.1080/03602532.2016.1188936. Epub 2016 Jun 9. Drug Metab Rev. 2016. PMID: 27278216 Review.

10

Stereoselective pharmacokinetics and metabolism of flobufen in guinea pigs.

Trejtnar F, Král R, Pávek P, Wsól V. Trejtnar F, et al. Among authors: pavek p. Chirality. 2003 Oct;15(8):724-9. doi: 10.1002/chir.10288. Chirality. 2003. PMID: 12923810

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