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Increased mTOR Signaling and Impaired Autophagic Flux Are Hallmarks of SARS-CoV-2 Infection.
Zambalde ÉP, Dias TL, Maktura GC, Amorim MR, Brenha B, Santos LN, Buscaratti L, Elston JGA, Mancini MCS, Pavan ICB, Toledo-Teixeira DA, Bispo-Dos-Santos K, Parise PL, Morelli AP, Silva LGSD, Castro ÍMS, Saccon TD, Mori MA, Granja F, Nakaya HI, Proenca-Modena JL, Marques-Souza H, Simabuco FM. Zambalde ÉP, et al. Among authors: pavan icb. Curr Issues Mol Biol. 2022 Dec 31;45(1):327-336. doi: 10.3390/cimb45010023. Curr Issues Mol Biol. 2022. PMID: 36661509 Free PMC article.
The Hallmarks of Flavonoids in Cancer.
Ponte LGS, Pavan ICB, Mancini MCS, da Silva LGS, Morelli AP, Severino MB, Bezerra RMN, Simabuco FM. Ponte LGS, et al. Among authors: pavan icb. Molecules. 2021 Apr 2;26(7):2029. doi: 10.3390/molecules26072029. Molecules. 2021. PMID: 33918290 Free PMC article. Review.
Characterization of the Interaction Between SARS-CoV-2 Membrane Protein (M) and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target.
Zambalde ÉP, Pavan ICB, Mancini MCS, Severino MB, Scudero OB, Morelli AP, Amorim MR, Bispo-Dos-Santos K, Góis MM, Toledo-Teixeira DA, Parise PL, Mauad T, Dolhnikoff M, Saldiva PHN, Marques-Souza H, Proenca-Modena JL, Ventura AM, Simabuco FM. Zambalde ÉP, et al. Among authors: pavan icb. Front Cell Infect Microbiol. 2022 May 23;12:849017. doi: 10.3389/fcimb.2022.849017. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35677658 Free PMC article.
Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways.
Morelli AP, Tortelli TC Jr, Pavan ICB, Silva FR, Granato DC, Peruca GF, Pauletti BA, Domingues RR, Bezerra RMN, De Moura LP, Paes Leme AF, Chammas R, Simabuco FM. Morelli AP, et al. Among authors: pavan icb. Int J Oncol. 2021 Jun;58(6):28. doi: 10.3892/ijo.2021.5208. Epub 2021 Apr 13. Int J Oncol. 2021. PMID: 33846781 Free PMC article.
STAT3 contributes to cisplatin resistance, modulating EMT markers, and the mTOR signaling in lung adenocarcinoma.
Morelli AP, Tortelli TC Jr, Mancini MCS, Pavan ICB, Silva LGS, Severino MB, Granato DC, Pestana NF, Ponte LGS, Peruca GF, Pauletti BA, Dos Santos DFG Jr, de Moura LP, Bezerra RMN, Leme AFP, Chammas R, Simabuco FM. Morelli AP, et al. Among authors: pavan icb. Neoplasia. 2021 Sep 17;23(10):1048-1058. doi: 10.1016/j.neo.2021.08.003. Online ahead of print. Neoplasia. 2021. PMID: 34543857 Free PMC article.
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