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Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53.
Lee JD, Menasche BL, Mavrikaki M, Uyemura MM, Hong SM, Kozlova N, Wei J, Alfajaro MM, Filler RB, Müller A, Saxena T, Posey RR, Cheung P, Muranen T, Heng YJ, Paulo JA, Wilen CB, Slack FJ. Lee JD, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2023 Sep 1:2023.08.31.555625. doi: 10.1101/2023.08.31.555625. bioRxiv. 2023. PMID: 37693555 Free PMC article. Updated. Preprint.
Combinatorial selective ER-phagy remodels the ER during neurogenesis.
Hoyer MJ, Capitanio C, Smith IR, Paoli JC, Bieber A, Jiang Y, Paulo JA, Gonzalez-Lozano MA, Baumeister W, Wilfling F, Schulman BA, Harper JW. Hoyer MJ, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2023 Nov 10:2023.06.26.546565. doi: 10.1101/2023.06.26.546565. bioRxiv. 2023. PMID: 37425907 Free PMC article. Updated. Preprint.
Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J. Chou CC, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2023 Mar 27:2023.03.27.534444. doi: 10.1101/2023.03.27.534444. bioRxiv. 2023. PMID: 37034684 Free PMC article. Preprint.
Targetable leukemia dependency on noncanonical PI3Kγ signaling.
Luo Q, Raulston EG, Prado MA, Wu X, Gritsman K, Yan K, Booth CAG, Xu R, van Galen P, Doench JG, Shimony S, Long HW, Neuberg DS, Paulo JA, Lane AA. Luo Q, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2023 Dec 15:2023.12.15.571909. doi: 10.1101/2023.12.15.571909. bioRxiv. 2023. PMID: 38328043 Free PMC article. Preprint.
Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer.
DeAngelo SL, Dziechciarz S, Solanki S, Shin M, Zhao L, Balia A, El-Derany MO, Das NK, Castillo C, Bell HN, Paulo JA, Zhang Y, Rossiter NJ, McCulla EC, He J, Talukder I, Schafer ZT, Neamati N, Mancias JD, Koutmos M, Shah YM. DeAngelo SL, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2024 Apr 1:2024.03.29.587381. doi: 10.1101/2024.03.29.587381. bioRxiv. 2024. PMID: 38617233 Free PMC article. Preprint.
297 results