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METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma.
Zeng X, Zhao F, Cui G, Zhang Y, Deshpande RA, Chen Y, Deng M, Kloeber JA, Shi Y, Zhou Q, Zhang C, Hou J, Kim W, Tu X, Yan Y, Xu Z, Chen L, Gao H, Guo G, Liu J, Zhu Q, Cao Y, Huang J, Wu Z, Zhu S, Yin P, Luo K, Mer G, Paull TT, Yuan J, Tao K, Lou Z. Zeng X, et al. Among authors: paull tt. Nat Cancer. 2022 Sep;3(9):1088-1104. doi: 10.1038/s43018-022-00429-3. Epub 2022 Sep 22. Nat Cancer. 2022. PMID: 36138131
ATM activation in the presence of oxidative stress.
Guo Z, Deshpande R, Paull TT. Guo Z, et al. Among authors: paull tt. Cell Cycle. 2010 Dec 15;9(24):4805-11. doi: 10.4161/cc.9.24.14323. Epub 2010 Dec 15. Cell Cycle. 2010. PMID: 21150274 Free PMC article.
EXD2 promotes homologous recombination by facilitating DNA end resection.
Broderick R, Nieminuszczy J, Baddock HT, Deshpande R, Gileadi O, Paull TT, McHugh PJ, Niedzwiedz W. Broderick R, et al. Among authors: paull tt. Nat Cell Biol. 2016 Mar;18(3):271-280. doi: 10.1038/ncb3303. Epub 2016 Jan 25. Nat Cell Biol. 2016. PMID: 26807646 Free PMC article.
117 results