Paulk NK - Search Results

1

Promoterless gene targeting without nucleases ameliorates haemophilia B in mice.

Barzel A, Paulk NK, Shi Y, Huang Y, Chu K, Zhang F, Valdmanis PN, Spector LP, Porteus MH, Gaensler KM, Kay MA. Barzel A, et al. Among authors: paulk nk. Nature. 2015 Jan 15;517(7534):360-4. doi: 10.1038/nature13864. Epub 2014 Oct 29. Nature. 2015. PMID: 25363772 Free PMC article.

2

Adeno-associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo.

Paulk NK, Wursthorn K, Wang Z, Finegold MJ, Kay MA, Grompe M. Paulk NK, et al. Hepatology. 2010 Apr;51(4):1200-8. doi: 10.1002/hep.23481. Hepatology. 2010. PMID: 20162619 Free PMC article.

3

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice.

Azuma H, Paulk N, Ranade A, Dorrell C, Al-Dhalimy M, Ellis E, Strom S, Kay MA, Finegold M, Grompe M. Azuma H, et al. Nat Biotechnol. 2007 Aug;25(8):903-10. doi: 10.1038/nbt1326. Epub 2007 Jul 29. Nat Biotechnol. 2007. PMID: 17664939 Free PMC article.

4

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.

Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA. Paulk NK, et al. Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25. Mol Ther. 2018. PMID: 29055620 Free PMC article.

5

An orange calcium-modulated bioluminescent indicator for non-invasive activity imaging.

Oh Y, Park Y, Cho JH, Wu H, Paulk NK, Liu LX, Kim N, Kay MA, Wu JC, Lin MZ. Oh Y, et al. Among authors: paulk nk. Nat Chem Biol. 2019 May;15(5):433-436. doi: 10.1038/s41589-019-0256-z. Epub 2019 Apr 1. Nat Chem Biol. 2019. PMID: 30936501 Free PMC article.

6

Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity.

Winters IP, Chiou SH, Paulk NK, McFarland CD, Lalgudi PV, Ma RK, Lisowski L, Connolly AJ, Petrov DA, Kay MA, Winslow MM. Winters IP, et al. Among authors: paulk nk. Nat Commun. 2017 Dec 12;8(1):2053. doi: 10.1038/s41467-017-01519-y. Nat Commun. 2017. PMID: 29233960 Free PMC article.

7

Rescue of Pompe disease in mice by AAV-mediated liver delivery of secretable acid α-glucosidase.

Puzzo F, Colella P, Biferi MG, Bali D, Paulk NK, Vidal P, Collaud F, Simon-Sola M, Charles S, Hardet R, Leborgne C, Meliani A, Cohen-Tannoudji M, Astord S, Gjata B, Sellier P, van Wittenberghe L, Vignaud A, Boisgerault F, Barkats M, Laforet P, Kay MA, Koeberl DD, Ronzitti G, Mingozzi F. Puzzo F, et al. Among authors: paulk nk. Sci Transl Med. 2017 Nov 29;9(418):eaam6375. doi: 10.1126/scitranslmed.aam6375. Sci Transl Med. 2017. PMID: 29187643 Free PMC article.

8

Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle.

Paulk NK, Pekrun K, Charville GW, Maguire-Nguyen K, Wosczyna MN, Xu J, Zhang Y, Lisowski L, Yoo B, Vilches-Moure JG, Lee GK, Shrager JB, Rando TA, Kay MA. Paulk NK, et al. Mol Ther Methods Clin Dev. 2018 Jul 24;10:144-155. doi: 10.1016/j.omtm.2018.06.001. eCollection 2018 Sep 21. Mol Ther Methods Clin Dev. 2018. PMID: 30101152 Free PMC article.

9

AAV-mediated gene targeting is significantly enhanced by transient inhibition of nonhomologous end joining or the proteasome in vivo.

Paulk NK, Loza LM, Finegold MJ, Grompe M. Paulk NK, et al. Hum Gene Ther. 2012 Jun;23(6):658-65. doi: 10.1089/hum.2012.038. Epub 2012 Jun 25. Hum Gene Ther. 2012. PMID: 22486314 Free PMC article.

10

In vivo selection of transplanted hepatocytes by pharmacological inhibition of fumarylacetoacetate hydrolase in wild-type mice.

Paulk NK, Wursthorn K, Haft A, Pelz C, Clarke G, Newell AH, Olson SB, Harding CO, Finegold MJ, Bateman RL, Witte JF, McClard R, Grompe M. Paulk NK, et al. Mol Ther. 2012 Oct;20(10):1981-7. doi: 10.1038/mt.2012.154. Epub 2012 Aug 7. Mol Ther. 2012. PMID: 22871666 Free PMC article.

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