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Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma.
Bischoff ME, Shamsaei B, Yang J, Secic D, Vemuri B, Reisz JA, D'Alessandro A, Bartolacci C, Adamczak R, Schmidt L, Wang J, Martines A, Biesiada J, Vest KE, Scaglioni PP, Plas DR, Patra KC, Gulati S, Figueroa JAL, Meller J, Cunningham JT, Czyzyk-Krzeska MF. Bischoff ME, et al. Among authors: patra kc. bioRxiv [Preprint]. 2024 Jan 19:2024.01.16.575895. doi: 10.1101/2024.01.16.575895. bioRxiv. 2024. PMID: 38293110 Free PMC article. Preprint.
Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms.
Chan GKL, Maisel S, Hwang YC, Pascual BC, Wolber RRB, Vu P, Patra KC, Bouhaddou M, Kenerson HL, Lim HC, Long D, Yeung RS, Sethupathy P, Swaney DL, Krogan NJ, Turnham RE, Riehle KJ, Scott JD, Bardeesy N, Gordan JD. Chan GKL, et al. Among authors: patra kc. Elife. 2023 Jan 24;12:e69521. doi: 10.7554/eLife.69521. Elife. 2023. PMID: 36692000 Free PMC article.
REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors.
Qiao S, Koh SB, Vivekanandan V, Salunke D, Patra KC, Zaganjor E, Ross K, Mizukami Y, Jeanfavre S, Chen A, Mino-Kenudson M, Ramaswamy S, Clish C, Haigis M, Bardeesy N, Ellisen LW. Qiao S, et al. Among authors: patra kc. Genes Dev. 2020 Jun 1;34(11-12):751-766. doi: 10.1101/gad.335166.119. Epub 2020 Apr 9. Genes Dev. 2020. PMID: 32273287 Free PMC article.
TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma.
Goyal L, Shi L, Liu LY, Fece de la Cruz F, Lennerz JK, Raghavan S, Leschiner I, Elagina L, Siravegna G, Ng RWS, Vu P, Patra KC, Saha SK, Uppot RN, Arellano R, Reyes S, Sagara T, Otsuki S, Nadres B, Shahzade HA, Dey-Guha I, Fetter IJ, Baiev I, Van Seventer EE, Murphy JE, Ferrone CR, Tanabe KK, Deshpande V, Harding JJ, Yaeger R, Kelley RK, Bardelli A, Iafrate AJ, Hahn WC, Benes CH, Ting DT, Hirai H, Getz G, Juric D, Zhu AX, Corcoran RB, Bardeesy N. Goyal L, et al. Among authors: patra kc. Cancer Discov. 2019 Aug;9(8):1064-1079. doi: 10.1158/2159-8290.CD-19-0182. Epub 2019 May 20. Cancer Discov. 2019. PMID: 31109923 Free PMC article.
AMPK-Mediated Lysosome Biogenesis in Lung Cancer Growth.
Patra KC, Weerasekara VK, Bardeesy N. Patra KC, et al. Cell Metab. 2019 Feb 5;29(2):238-240. doi: 10.1016/j.cmet.2018.12.011. Epub 2019 Jan 3. Cell Metab. 2019. PMID: 30612899 Free article.
35 results