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Statistical power in COVID-19 case-control host genomic study design.
Lin YC, Brooks JD, Bull SB, Gagnon F, Greenwood CMT, Hung RJ, Lawless J, Paterson AD, Sun L, Strug LJ; Genetic Epidemiology Committee of the Canadian COVID Genomics Network (CanCOGeN) HostSeq Project. Lin YC, et al. Among authors: paterson ad. Genome Med. 2020 Dec 28;12(1):115. doi: 10.1186/s13073-020-00818-2. Genome Med. 2020. PMID: 33371892 Free PMC article.
Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity.
Wither J, Cai YC, Lim S, McKenzie T, Roslin N, Claudio JO, Cooper GS, Hudson TJ, Paterson AD, Greenwood CM, Gladman D, Pope J, Pineau CA, Smith CD, Hanly JG, Peschken C, Boire G; CaNIOS Investigators; Fortin PR. Wither J, et al. Among authors: paterson ad. Arthritis Res Ther. 2008;10(5):R108. doi: 10.1186/ar2505. Epub 2008 Sep 10. Arthritis Res Ther. 2008. PMID: 18783591 Free PMC article.
Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.
Mrkonjic M, Roslin NM, Greenwood CM, Raptis S, Pollett A, Laird PW, Pethe VV, Chiang T, Daftary D, Dicks E, Thibodeau SN, Gallinger S, Parfrey PS, Younghusband HB, Potter JD, Hudson TJ, McLaughlin JR, Green RC, Zanke BW, Newcomb PA, Paterson AD, Bapat B. Mrkonjic M, et al. Among authors: paterson ad. PLoS One. 2010 Oct 13;5(10):e13314. doi: 10.1371/journal.pone.0013314. PLoS One. 2010. PMID: 20967208 Free PMC article.
BR-squared: a practical solution to the winner's curse in genome-wide scans.
Sun L, Dimitromanolakis A, Faye LL, Paterson AD, Waggott D; DCCT/EDIC Research Group; Bull SB. Sun L, et al. Among authors: paterson ad. Hum Genet. 2011 May;129(5):545-52. doi: 10.1007/s00439-011-0948-2. Epub 2011 Jan 19. Hum Genet. 2011. PMID: 21246217 Free PMC article.
A genome-wide linkage study of mammographic density, a risk factor for breast cancer.
Greenwood CM, Paterson AD, Linton L, Andrulis IL, Apicella C, Dimitromanolakis A, Kriukov V, Martin LJ, Salleh A, Samiltchuk E, Parekh RV, Southey MC, John EM, Hopper JL, Boyd NF, Rommens JM. Greenwood CM, et al. Among authors: paterson ad. Breast Cancer Res. 2011;13(6):R132. doi: 10.1186/bcr3078. Epub 2011 Dec 21. Breast Cancer Res. 2011. PMID: 22188651 Free PMC article.
352 results