Patel KJ - Search Results

1

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.

Burgos-Barragan G, Wit N, Meiser J, Dingler FA, Pietzke M, Mulderrig L, Pontel LB, Rosado IV, Brewer TF, Cordell RL, Monks PS, Chang CJ, Vazquez A, Patel KJ. Burgos-Barragan G, et al. Among authors: patel kj. Nature. 2017 Aug 31;548(7669):549-554. doi: 10.1038/nature23481. Epub 2017 Aug 16. Nature. 2017. PMID: 28813411 Free PMC article.

2

The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair.

Rosado IV, Niedzwiedz W, Alpi AF, Patel KJ. Rosado IV, et al. Among authors: patel kj. Nucleic Acids Res. 2009 Jul;37(13):4360-70. doi: 10.1093/nar/gkp365. Epub 2009 May 21. Nucleic Acids Res. 2009. PMID: 19465393 Free PMC article.

3

Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway.

Pace P, Mosedale G, Hodskinson MR, Rosado IV, Sivasubramaniam M, Patel KJ. Pace P, et al. Among authors: patel kj. Science. 2010 Jul 9;329(5988):219-23. doi: 10.1126/science.1192277. Epub 2010 Jun 10. Science. 2010. PMID: 20538911

4

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia.

Crossan GP, van der Weyden L, Rosado IV, Langevin F, Gaillard PHL, McIntyre RE; Sanger Mouse Genetics Project; Gallagher F, Kettunen MI, Lewis DY, Brindle K, Arends MJ, Adams DJ, Patel KJ. Crossan GP, et al. Among authors: patel kj. Nat Genet. 2011 Feb;43(2):147-52. doi: 10.1038/ng.752. Epub 2011 Jan 16. Nat Genet. 2011. PMID: 21240276 Free PMC article.

5

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

Langevin F, Crossan GP, Rosado IV, Arends MJ, Patel KJ. Langevin F, et al. Among authors: patel kj. Nature. 2011 Jul 6;475(7354):53-8. doi: 10.1038/nature10192. Nature. 2011. PMID: 21734703

6

Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway.

Rosado IV, Langevin F, Crossan GP, Takata M, Patel KJ. Rosado IV, et al. Among authors: patel kj. Nat Struct Mol Biol. 2011 Nov 13;18(12):1432-4. doi: 10.1038/nsmb.2173. Nat Struct Mol Biol. 2011. PMID: 22081012

7

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.

Garaycoechea JI, Crossan GP, Langevin F, Daly M, Arends MJ, Patel KJ. Garaycoechea JI, et al. Among authors: patel kj. Nature. 2012 Sep 27;489(7417):571-5. doi: 10.1038/nature11368. Epub 2012 Aug 26. Nature. 2012. PMID: 22922648

8

Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.

Pontel LB, Rosado IV, Burgos-Barragan G, Garaycoechea JI, Yu R, Arends MJ, Chandrasekaran G, Broecker V, Wei W, Liu L, Swenberg JA, Crossan GP, Patel KJ. Pontel LB, et al. Among authors: patel kj. Mol Cell. 2015 Oct 1;60(1):177-88. doi: 10.1016/j.molcel.2015.08.020. Epub 2015 Sep 24. Mol Cell. 2015. PMID: 26412304 Free PMC article.

9

Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium.

Pontel LB, Langenick J, Rosado IV, Zhang XY, Traynor D, Kay RR, Patel KJ. Pontel LB, et al. Among authors: patel kj. J Cell Sci. 2016 Dec 15;129(24):4449-4454. doi: 10.1242/jcs.196337. Epub 2016 Nov 21. J Cell Sci. 2016. PMID: 27872153 Free PMC article.

10

Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde in Living Cells.

Bruemmer KJ, Walvoord RR, Brewer TF, Burgos-Barragan G, Wit N, Pontel LB, Patel KJ, Chang CJ. Bruemmer KJ, et al. Among authors: patel kj. J Am Chem Soc. 2017 Apr 19;139(15):5338-5350. doi: 10.1021/jacs.6b12460. Epub 2017 Apr 4. J Am Chem Soc. 2017. PMID: 28375637 Free PMC article.

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