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IKK2 inhibition attenuates laser-induced choroidal neovascularization.
Lu H, Lu Q, Gaddipati S, Kasetti RB, Wang W, Pasparakis M, Kaplan HJ, Li Q. Lu H, et al. Among authors: pasparakis m. PLoS One. 2014 Jan 28;9(1):e87530. doi: 10.1371/journal.pone.0087530. eCollection 2014. PLoS One. 2014. PMID: 24489934 Free PMC article.
Epithelial NEMO links innate immunity to chronic intestinal inflammation.
Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Neurath MF, Pasparakis M. Nenci A, et al. Among authors: pasparakis m. Nature. 2007 Mar 29;446(7135):557-61. doi: 10.1038/nature05698. Epub 2007 Mar 14. Nature. 2007. PMID: 17361131 Free article.
Hepatocyte IKK2 protects Mdr2-/- mice from chronic liver failure.
Ehlken H, Kondylis V, Heinrichsdorff J, Ochoa-Callejero L, Roskams T, Pasparakis M. Ehlken H, et al. Among authors: pasparakis m. PLoS One. 2011;6(10):e25942. doi: 10.1371/journal.pone.0025942. Epub 2011 Oct 14. PLoS One. 2011. PMID: 22022477 Free PMC article.
Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury.
Luedde T, Assmus U, Wüstefeld T, Meyer zu Vilsendorf A, Roskams T, Schmidt-Supprian M, Rajewsky K, Brenner DA, Manns MP, Pasparakis M, Trautwein C. Luedde T, et al. Among authors: pasparakis m. J Clin Invest. 2005 Apr;115(4):849-59. doi: 10.1172/JCI23493. Epub 2005 Mar 17. J Clin Invest. 2005. PMID: 15776110 Free PMC article.
IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver.
Luedde T, Heinrichsdorff J, de Lorenzi R, De Vos R, Roskams T, Pasparakis M. Luedde T, et al. Among authors: pasparakis m. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9733-8. doi: 10.1073/pnas.0800198105. Epub 2008 Jul 7. Proc Natl Acad Sci U S A. 2008. PMID: 18606991 Free PMC article.
195 results