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Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy.
Roos J, Peters M, Maucher IV, Kühn B, Fettel J, Hellmuth N, Brat C, Sommer B, Urbschat A, Piesche M, Vogel A, Proschak E, Blöcher R, Buscató E, Häfner AK, Matrone C, Werz O, Heidler J, Wittig I, Angioni C, Geisslinger G, Parnham MJ, Zacharowski K, Steinhilber D, Maier TJ. Roos J, et al. Among authors: parnham mj. Antioxid Redox Signal. 2018 May 10;28(14):1265-1285. doi: 10.1089/ars.2017.7155. Epub 2017 Sep 8. Antioxid Redox Signal. 2018. PMID: 28699354
Pharmacokinetics of non-intravenous formulations of fentanyl.
Lötsch J, Walter C, Parnham MJ, Oertel BG, Geisslinger G. Lötsch J, et al. Among authors: parnham mj. Clin Pharmacokinet. 2013 Jan;52(1):23-36. doi: 10.1007/s40262-012-0016-7. Clin Pharmacokinet. 2013. PMID: 23100195 Review.
Common non-epigenetic drugs as epigenetic modulators.
Lötsch J, Schneider G, Reker D, Parnham MJ, Schneider P, Geisslinger G, Doehring A. Lötsch J, et al. Among authors: parnham mj. Trends Mol Med. 2013 Dec;19(12):742-53. doi: 10.1016/j.molmed.2013.08.006. Epub 2013 Sep 18. Trends Mol Med. 2013. PMID: 24054876 Review.
R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice.
Schmitz K, de Bruin N, Bishay P, Männich J, Häussler A, Altmann C, Ferreirós N, Lötsch J, Ultsch A, Parnham MJ, Geisslinger G, Tegeder I. Schmitz K, et al. Among authors: parnham mj. EMBO Mol Med. 2014 Nov;6(11):1398-422. doi: 10.15252/emmm.201404168. EMBO Mol Med. 2014. PMID: 25269445 Free PMC article.
Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.
Lehmann C, Homann J, Ball AK, Blöcher R, Kleinschmidt TK, Basavarajappa D, Angioni C, Ferreirós N, Häfner AK, Rådmark O, Proschak E, Haeggström JZ, Geisslinger G, Parnham MJ, Steinhilber D, Kahnt AS. Lehmann C, et al. Among authors: parnham mj. FASEB J. 2015 Dec;29(12):5029-43. doi: 10.1096/fj.15-275487. Epub 2015 Aug 19. FASEB J. 2015. PMID: 26289316
Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?
Roos J, Grösch S, Werz O, Schröder P, Ziegler S, Fulda S, Paulus P, Urbschat A, Kühn B, Maucher I, Fettel J, Vorup-Jensen T, Piesche M, Matrone C, Steinhilber D, Parnham MJ, Maier TJ. Roos J, et al. Among authors: parnham mj. Pharmacol Ther. 2016 Jan;157:43-64. doi: 10.1016/j.pharmthera.2015.11.001. Epub 2015 Nov 6. Pharmacol Ther. 2016. PMID: 26549540 Review.
Drug Repurposing for the Development of Novel Analgesics.
Sisignano M, Parnham MJ, Geisslinger G. Sisignano M, et al. Among authors: parnham mj. Trends Pharmacol Sci. 2016 Mar;37(3):172-183. doi: 10.1016/j.tips.2015.11.006. Epub 2015 Dec 17. Trends Pharmacol Sci. 2016. PMID: 26706620
Pparγ Expression in T Cells as a Prognostic Marker of Sepsis.
Brenneis M, Aghajaanpour R, Knape T, Sha LK, Neb H, Meybohm P, Zacharowski K, Hauser IA, Büttner S, Parnham MJ, Brüne B, von Knethen A. Brenneis M, et al. Among authors: parnham mj. Shock. 2016 Jun;45(6):591-7. doi: 10.1097/SHK.0000000000000568. Shock. 2016. PMID: 26796570
210 results