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Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo.
Parmar A, Lakshminarayanan R, Iyer A, Mayandi V, Leng Goh ET, Lloyd DG, Chalasani MLS, Verma NK, Prior SH, Beuerman RW, Madder A, Taylor EJ, Singh I. Parmar A, et al. J Med Chem. 2018 Mar 8;61(5):2009-2017. doi: 10.1021/acs.jmedchem.7b01634. Epub 2018 Feb 15. J Med Chem. 2018. PMID: 29363971
Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA).
Malkawi R, Iyer A, Parmar A, Lloyd DG, Leng Goh ET, Taylor EJ, Sarmad S, Madder A, Lakshminarayanan R, Singh I. Malkawi R, et al. Among authors: parmar a. Pharmaceutics. 2018 Oct 11;10(4):183. doi: 10.3390/pharmaceutics10040183. Pharmaceutics. 2018. PMID: 30314324 Free PMC article.
Mode of action of teixobactins in cellular membranes.
Shukla R, Medeiros-Silva J, Parmar A, Vermeulen BJA, Das S, Paioni AL, Jekhmane S, Lorent J, Bonvin AMJJ, Baldus M, Lelli M, Veldhuizen EJA, Breukink E, Singh I, Weingarth M. Shukla R, et al. Among authors: parmar a. Nat Commun. 2020 Jun 5;11(1):2848. doi: 10.1038/s41467-020-16600-2. Nat Commun. 2020. PMID: 32503964 Free PMC article.
Application of Multi-Criteria Decision Analysis (MCDA) to Prioritize Real-World Evidence Studies for Health Technology Management: Outcomes and Lessons Learned by the Canadian Real-World Evidence for Value of Cancer Drugs (CanREValue) Collaboration.
Takhar P, Geirnaert M, Gavura S, Beca J, Mercer RE, Denburg A, Muñoz C, Tadrous M, Parmar A, Dionne F, Boehm D, Chambers C, Craig E, Trudeau M, Cheung MC, Houlihan J, McDonald V, Pechlivanoglou P, Taylor M, Wasylenko E, Wranik WD, Chan KKW. Takhar P, et al. Among authors: parmar a. Curr Oncol. 2024 Apr 1;31(4):1876-1898. doi: 10.3390/curroncol31040141. Curr Oncol. 2024. PMID: 38668044 Free PMC article.
440 results