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Preclinical Analysis of Candidate Anti-Human CD79 Therapeutic Antibodies Using a Humanized CD79 Mouse Model.
J Immunol. 2022 Apr 1;208(7):1566-1584. doi: 10.4049/jimmunol.2101056. Epub 2022 Mar 23.
J Immunol. 2022.
PMID: 35321883
Free PMC article.
B cell antigen presentation is sufficient to drive neuroinflammation in an animal model of multiple sclerosis.
Parker Harp CR, Archambault AS, Sim J, Ferris ST, Mikesell RJ, Koni PA, Shimoda M, Linington C, Russell JH, Wu GF.
Parker Harp CR, et al.
J Immunol. 2015 Jun 1;194(11):5077-84. doi: 10.4049/jimmunol.1402236. Epub 2015 Apr 20.
J Immunol. 2015.
PMID: 25895531
Free PMC article.
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B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis.
Parker Harp CR, Archambault AS, Sim J, Shlomchik MJ, Russell JH, Wu GF.
Parker Harp CR, et al.
PLoS One. 2018 Jun 26;13(6):e0199694. doi: 10.1371/journal.pone.0199694. eCollection 2018.
PLoS One. 2018.
PMID: 29944721
Free PMC article.
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Neutrophils promote VLA-4-dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation.
Parker Harp CR, Archambault AS, Cheung M, Williams JW, Czepielewski RS, Duncker PC, Kilgore AJ, Miller AT, Segal BM, Kim AHJ, Randolph GJ, Wu GF.
Parker Harp CR, et al.
Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24221-24230. doi: 10.1073/pnas.1909098116. Epub 2019 Nov 7.
Proc Natl Acad Sci U S A. 2019.
PMID: 31699814
Free PMC article.
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Optic Neuritis: A Model for the Immuno-pathogenesis of Central Nervous System Inflammatory Demyelinating Diseases.
Wu GF, Parker Harp CR, Shindler KS.
Wu GF, et al. Among authors: parker harp cr.
Curr Immunol Rev. 2015;11(2):85-92. doi: 10.2174/1573395511666150707181644.
Curr Immunol Rev. 2015.
PMID: 29399010
Free PMC article.
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Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis.
Himmelbauer MK, Bajrami B, Basile R, Capacci A, Chen T, Choi CK, Gilfillan R, Gonzalez-Lopez de Turiso F, Gu C, Hoemberger M, Johnson DS, Jones JH, Kadakia E, Kirkland M, Lin EY, Liu Y, Ma B, Magee T, Mantena S, Marx IE, Metrick CM, Mingueneau M, Murugan P, Muste CA, Nadella P, Nevalainen M, Parker Harp CR, Pattaropong V, Pietrasiewicz A, Prince RJ, Purgett TJ, Santoro JC, Schulz J, Sciabola S, Tang H, Vandeveer HG, Wang T, Yousaf Z, Helal CJ, Hopkins BT.
Himmelbauer MK, et al. Among authors: parker harp cr.
J Med Chem. 2024 May 7. doi: 10.1021/acs.jmedchem.4c00220. Online ahead of print.
J Med Chem. 2024.
PMID: 38712838
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