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Imidazoline-I2 PET Tracers in Neuroimaging.
Parker CA, Nutt DJ, Tyacke RJ. Parker CA, et al. Int J Mol Sci. 2023 Jun 6;24(12):9787. doi: 10.3390/ijms24129787. Int J Mol Sci. 2023. PMID: 37372936 Free PMC article. Review.
Evaluation and initial in vitro and ex vivo characterization of the potential positron emission tomography ligand, BU99008 (2-(4,5-dihydro-1H-imidazol-2-yl)-1- methyl-1H-indole), for the imidazoline₂ binding site.
Tyacke RJ, Fisher A, Robinson ES, Grundt P, Turner EM, Husbands SM, Hudson AL, Parker CA, Nutt DJ. Tyacke RJ, et al. Among authors: parker ca. Synapse. 2012 Jun;66(6):542-51. doi: 10.1002/syn.21541. Epub 2012 Feb 22. Synapse. 2012. PMID: 22290740
Imaging imidazoline-I2 binding sites in porcine brain using 11C-BU99008.
Kealey S, Turner EM, Husbands SM, Salinas CA, Jakobsen S, Tyacke RJ, Nutt DJ, Parker CA, Gee AD. Kealey S, et al. Among authors: parker ca. J Nucl Med. 2013 Jan;54(1):139-44. doi: 10.2967/jnumed.112.108258. Epub 2012 Dec 5. J Nucl Med. 2013. PMID: 23223380 Free article.
Astrocyte reactivity with late-onset cognitive impairment assessed in vivo using 11C-BU99008 PET and its relationship with amyloid load.
Calsolaro V, Matthews PM, Donat CK, Livingston NR, Femminella GD, Guedes SS, Myers J, Fan Z, Tyacke RJ, Venkataraman AV, Perneczky R, Gunn R, Rabiner EA, Gentleman S, Parker CA, Murphy PS, Wren PB, Hinz R, Sastre M, Nutt DJ, Edison P. Calsolaro V, et al. Among authors: parker ca. Mol Psychiatry. 2021 Oct;26(10):5848-5855. doi: 10.1038/s41380-021-01193-z. Epub 2021 Jul 15. Mol Psychiatry. 2021. PMID: 34267329 Free PMC article.
Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals.
Livingston NR, Calsolaro V, Hinz R, Nowell J, Raza S, Gentleman S, Tyacke RJ, Myers J, Venkataraman AV, Perneczky R, Gunn RN, Rabiner EA, Parker CA, Murphy PS, Wren PB, Nutt DJ, Matthews PM, Edison P. Livingston NR, et al. Among authors: parker ca. Mol Psychiatry. 2022 Apr;27(4):2019-2029. doi: 10.1038/s41380-021-01429-y. Epub 2022 Feb 7. Mol Psychiatry. 2022. PMID: 35125495 Free PMC article.
124 results