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Safety pharmacology--current and emerging concepts.
Hamdam J, Sethu S, Smith T, Alfirevic A, Alhaidari M, Atkinson J, Ayala M, Box H, Cross M, Delaunois A, Dermody A, Govindappa K, Guillon JM, Jenkins R, Kenna G, Lemmer B, Meecham K, Olayanju A, Pestel S, Rothfuss A, Sidaway J, Sison-Young R, Smith E, Stebbings R, Tingle Y, Valentin JP, Williams A, Williams D, Park K, Goldring C. Hamdam J, et al. Among authors: park k. Toxicol Appl Pharmacol. 2013 Dec 1;273(2):229-41. doi: 10.1016/j.taap.2013.04.039. Epub 2013 Jun 1. Toxicol Appl Pharmacol. 2013. PMID: 23732082 Review.
Investigation of toxic metabolites during drug development.
Park K, Williams DP, Naisbitt DJ, Kitteringham NR, Pirmohamed M. Park K, et al. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):425-34. doi: 10.1016/j.taap.2005.02.029. Toxicol Appl Pharmacol. 2005. PMID: 15996699 Review.
Immunogenicity to biologics: mechanisms, prediction and reduction.
Sethu S, Govindappa K, Alhaidari M, Pirmohamed M, Park K, Sathish J. Sethu S, et al. Among authors: park k. Arch Immunol Ther Exp (Warsz). 2012 Oct;60(5):331-44. doi: 10.1007/s00005-012-0189-7. Epub 2012 Aug 29. Arch Immunol Ther Exp (Warsz). 2012. PMID: 22930363 Free article. Review.
Immunoglobulin G1 and immunoglobulin G4 antibodies in multiple sclerosis patients treated with IFNβ interact with the endogenous cytokine and activate complement.
Sethu S, Govindappa K, Quinn P, Wadhwa M, Stebbings R, Boggild M, Naisbitt D, Kimber I, Pirmohamed M, Park K, Sathish J. Sethu S, et al. Among authors: park k. Clin Immunol. 2013 Aug;148(2):177-85. doi: 10.1016/j.clim.2013.05.008. Epub 2013 May 22. Clin Immunol. 2013. PMID: 23770627 Free PMC article.
Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study.
Bell CC, Dankers ACA, Lauschke VM, Sison-Young R, Jenkins R, Rowe C, Goldring CE, Park K, Regan SL, Walker T, Schofield C, Baze A, Foster AJ, Williams DP, van de Ven AWM, Jacobs F, Houdt JV, Lähteenmäki T, Snoeys J, Juhila S, Richert L, Ingelman-Sundberg M. Bell CC, et al. Among authors: park k. Toxicol Sci. 2018 Apr 1;162(2):655-666. doi: 10.1093/toxsci/kfx289. Toxicol Sci. 2018. PMID: 29329425 Free PMC article.
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