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Prepubertal children with obesity have high free IGF-1 levels and accelerated growth despite reduced pappalysin levels.
Martín-Rivada Á, Martos-Moreno GÁ, Guerra-Cantera S, Campillo-Calatayud A, Oxvig C, Frystyk J, Chowen JA, Barrios V, Argente J. Martín-Rivada Á, et al. J Clin Endocrinol Metab. 2024 Apr 25:dgae288. doi: 10.1210/clinem/dgae288. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 38662803
OBJECTIVE: We aimed to determine the effects of childhood obesity and weight reduction on serum levels of PAPP-A, PAPP-A2, STC1 and STC2 and their relationship with IGF bioavailability, growth, and other components of the GH-IGF system. ...RESULTS: Children with obe …
OBJECTIVE: We aimed to determine the effects of childhood obesity and weight reduction on serum levels of PAPP-A, PAPP-A2, STC …
Combined first-trimester screening and invasive diagnostics for atypical chromosomal aberrations: Danish nationwide data on prenatal profiles and detection compared with NIPT.
Gadsbøll K, Vogel I, Kristensen SE, Pedersen LH, Hyett J; Danish Cytogenetic Central Register study group; Petersen OB. Gadsbøll K, et al. Ultrasound Obstet Gynecol. 2024 Apr 20. doi: 10.1002/uog.27667. Online ahead of print. Ultrasound Obstet Gynecol. 2024. PMID: 38642365
In pregnancies with maternal age <30 years, NT <95(th) percentile, PAPP-A MoM 1, or trisomy 21 risk 1 in 1000, the prevalence of pCNVs significantly exceeded the prevalence of trisomies 21, 18, and 13. Pregnancies affected by a pCNV had significantly increased …
In pregnancies with maternal age <30 years, NT <95(th) percentile, PAPP-A MoM 1, or trisomy 21 risk 1 in 1000, the preva …
Association between aneuploidy screening analytes and adverse outcomes in twin gestations.
Yamasato K, Ono A. Yamasato K, et al. J Perinat Med. 2024 Apr 19. doi: 10.1515/jpm-2023-0499. Online ahead of print. J Perinat Med. 2024. PMID: 38634781
METHODS: This cohort included twins delivered at a tertiary care hospital from 2009 to 2017. Abnormal levels of pregnancy associated plasma protein (PAPP-A), first and second trimester human chorionic gonadotropin (hCG), alpha fetoprotein (AFP), …
METHODS: This cohort included twins delivered at a tertiary care hospital from 2009 to 2017. Abnormal levels of pregnancy associat …
Unveiling the Role of Pregnancy-Associated Plasma Protein A (PAPP-A) in Pregnancy-Associated Breast Cancer: A Comprehensive Review.
Patel A, Dewani D, Jaiswal A, Reddy LS, Yadav P, Sethi N. Patel A, et al. Cureus. 2024 Mar 16;16(3):e56269. doi: 10.7759/cureus.56269. eCollection 2024 Mar. Cureus. 2024. PMID: 38623138 Free PMC article. Review.
Pregnancy-associated breast cancer (PABC) presents unique challenges due to its occurrence during or shortly after pregnancy. Pregnancy-associated plasma protein A (PAPP-A) has emerged as a potential biomarker and reg …
Pregnancy-associated breast cancer (PABC) presents unique challenges due to its occurrence during or shortly after pregnancy. …
Navigating Uncertain Waters: First-Trimester Screening's Role in Identifying Neonatal Complications.
Swiercz G, Zmelonek-Znamirowska A, Szwabowicz K, Armanska J, Detka K, Mlodawska M, Mlodawski J. Swiercz G, et al. J Clin Med. 2024 Mar 29;13(7):1982. doi: 10.3390/jcm13071982. J Clin Med. 2024. PMID: 38610747 Free PMC article.
Methods: This study encompassed 1164 patients who underwent first-trimester screening, including patient history, ultrasound examinations, and biochemical tests for pregnancy-associated plasma protein-A (PAPP-A) and the free beta-H …
Methods: This study encompassed 1164 patients who underwent first-trimester screening, including patient history, ultrasound examinations, a …
3,408 results