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Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import.
Sci Adv. 2023 Aug 18;9(33):eadi5548. doi: 10.1126/sciadv.adi5548. Epub 2023 Aug 16.
Sci Adv. 2023.
PMID: 37585529
Free PMC article.
Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls.
Simkin D, Papakis V, Bustos BI, Ambrosi CM, Ryan SJ, Baru V, Williams LA, Dempsey GT, McManus OB, Landers JE, Lubbe SJ, George AL Jr, Kiskinis E.
Simkin D, et al. Among authors: papakis v.
Stem Cell Reports. 2022 Apr 12;17(4):993-1008. doi: 10.1016/j.stemcr.2022.02.008. Epub 2022 Mar 10.
Stem Cell Reports. 2022.
PMID: 35276091
Free PMC article.
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Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons.
Álvarez Z, Ortega JA, Sato K, Sasselli IR, Kolberg-Edelbrock AN, Qiu R, Marshall KA, Nguyen TP, Smith CS, Quinlan KA, Papakis V, Syrgiannis Z, Sather NA, Musumeci C, Engel E, Stupp SI, Kiskinis E.
Álvarez Z, et al. Among authors: papakis v.
Cell Stem Cell. 2023 Feb 2;30(2):219-238.e14. doi: 10.1016/j.stem.2022.12.010. Epub 2023 Jan 12.
Cell Stem Cell. 2023.
PMID: 36638801
Free PMC article.
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Uncoupling gene expression noise along the central dogma using genome engineered human cell lines.
Quarton T, Kang T, Papakis V, Nguyen K, Nowak C, Li Y, Bleris L.
Quarton T, et al. Among authors: papakis v.
Nucleic Acids Res. 2020 Sep 18;48(16):9406-9413. doi: 10.1093/nar/gkaa668.
Nucleic Acids Res. 2020.
PMID: 32810265
Free PMC article.
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