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Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations.
Mannarino L, Mirimao F, Panini N, Paracchini L, Marchini S, Beltrame L, Amodeo R, Grosso F, Libener R, De Simone I, Ceresoli GL, Zucali PA, Lupi M, D'Incalci M. Mannarino L, et al. Among authors: panini n. Cell Death Dis. 2022 Jul 15;13(7):612. doi: 10.1038/s41419-022-05073-4. Cell Death Dis. 2022. PMID: 35840560 Free PMC article.
Promising in vivo efficacy of the BET bromodomain inhibitor OTX015/MK-8628 in malignant pleural mesothelioma xenografts.
Vázquez R, Licandro SA, Astorgues-Xerri L, Lettera E, Panini N, Romano M, Erba E, Ubezio P, Bello E, Libener R, Orecchia S, Grosso F, Riveiro ME, Cvitkovic E, Bekradda M, D'Incalci M, Frapolli R. Vázquez R, et al. Among authors: panini n. Int J Cancer. 2017 Jan 1;140(1):197-207. doi: 10.1002/ijc.30412. Epub 2016 Sep 19. Int J Cancer. 2017. PMID: 27594045 Free article.
The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus.
Vázquez R, Riveiro ME, Astorgues-Xerri L, Odore E, Rezai K, Erba E, Panini N, Rinaldi A, Kwee I, Beltrame L, Bekradda M, Cvitkovic E, Bertoni F, Frapolli R, D'Incalci M. Vázquez R, et al. Among authors: panini n. Oncotarget. 2017 Jan 31;8(5):7598-7613. doi: 10.18632/oncotarget.13814. Oncotarget. 2017. PMID: 27935867 Free PMC article.
Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms.
Romano M, Della Porta MG, Gallì A, Panini N, Licandro SA, Bello E, Craparotta I, Rosti V, Bonetti E, Tancredi R, Rossi M, Mannarino L, Marchini S, Porcu L, Galmarini CM, Zambelli A, Zecca M, Locatelli F, Cazzola M, Biondi A, Rambaldi A, Allavena P, Erba E, D'Incalci M. Romano M, et al. Among authors: panini n. Br J Cancer. 2017 Jan;116(3):335-343. doi: 10.1038/bjc.2016.424. Epub 2017 Jan 10. Br J Cancer. 2017. PMID: 28072764 Free PMC article.
Mechanism of action of trabectedin in desmoplastic small round cell tumor cells.
Uboldi S, Craparotta I, Colella G, Ronchetti E, Beltrame L, Vicario S, Marchini S, Panini N, Dagrada G, Bozzi F, Pilotti S, Galmarini CM, D'Incalci M, Gatta R. Uboldi S, et al. Among authors: panini n. BMC Cancer. 2017 Feb 6;17(1):107. doi: 10.1186/s12885-017-3091-1. BMC Cancer. 2017. PMID: 28166781 Free PMC article.
Trabectedin is a novel chemotherapy agent for diffuse large B cell lymphoma.
Spriano F, Chung EY, Panini N, Cascione L, Rinaldi A, Erba E, Stathis A, D'Incalci M, Bertoni F, Gatta R. Spriano F, et al. Among authors: panini n. Br J Haematol. 2019 Mar;184(6):1022-1025. doi: 10.1111/bjh.15212. Epub 2018 Apr 2. Br J Haematol. 2019. PMID: 29611184 Free article. No abstract available.
The soluble glycoprotein NMB (GPNMB) produced by macrophages induces cancer stemness and metastasis via CD44 and IL-33.
Liguori M, Digifico E, Vacchini A, Avigni R, Colombo FS, Borroni EM, Farina FM, Milanesi S, Castagna A, Mannarino L, Craparotta I, Marchini S, Erba E, Panini N, Tamborini M, Rimoldi V, Allavena P, Belgiovine C. Liguori M, et al. Among authors: panini n. Cell Mol Immunol. 2021 Mar;18(3):711-722. doi: 10.1038/s41423-020-0501-0. Epub 2020 Jul 29. Cell Mol Immunol. 2021. PMID: 32728200 Free PMC article.
Mechanisms of responsiveness to and resistance against trabectedin in murine models of human myxoid liposarcoma.
Mannarino L, Craparotta I, Ballabio S, Frapolli R, Meroni M, Bello E, Panini N, Callari M, Sanfilippo R, Casali PG, Barisella M, Fabbroni C, Marchini S, D'Incalci M. Mannarino L, et al. Among authors: panini n. Genomics. 2021 Sep;113(5):3439-3448. doi: 10.1016/j.ygeno.2021.07.028. Epub 2021 Jul 30. Genomics. 2021. PMID: 34339817 Free article.
PEGylated recombinant human hyaluronidase (PEGPH20) pre-treatment improves intra-tumour distribution and efficacy of paclitaxel in preclinical models.
Morosi L, Meroni M, Ubezio P, Fuso Nerini I, Minoli L, Porcu L, Panini N, Colombo M, Blouw B, Kang DW, Davoli E, Zucchetti M, D'Incalci M, Frapolli R. Morosi L, et al. Among authors: panini n. J Exp Clin Cancer Res. 2021 Sep 10;40(1):286. doi: 10.1186/s13046-021-02070-x. J Exp Clin Cancer Res. 2021. PMID: 34507591 Free PMC article.
39 results