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Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.
Wang Q, Kim SY, Matsushita H, Wang Z, Pandyarajan V, Matsuda M, Ohashi K, Tsuchiya T, Roh YS, Kiani C, Zhao Y, Chan M, Devkota S, Lu SC, Hayashi T, Carson DA, Seki E. Wang Q, et al. Among authors: pandyarajan v. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2020868118. doi: 10.1073/pnas.2020868118. Epub 2020 Dec 21. Proc Natl Acad Sci U S A. 2021. PMID: 33443222 Free PMC article.
Protective hinge in insulin opens to enable its receptor engagement.
Menting JG, Yang Y, Chan SJ, Phillips NB, Smith BJ, Whittaker J, Wickramasinghe NP, Whittaker LJ, Pandyarajan V, Wan ZL, Yadav SP, Carroll JM, Strokes N, Roberts CT Jr, Ismail-Beigi F, Milewski W, Steiner DF, Chauhan VS, Ward CW, Weiss MA, Lawrence MC. Menting JG, et al. Among authors: pandyarajan v. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):E3395-404. doi: 10.1073/pnas.1412897111. Epub 2014 Aug 4. Proc Natl Acad Sci U S A. 2014. PMID: 25092300 Free PMC article.
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