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Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors.
Future Med Chem. 2019 Jun;11(11):1245-1258. doi: 10.4155/fmc-2018-0535. Epub 2019 Apr 12.
Future Med Chem. 2019.
PMID: 30974972
An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain.
Ronsisvalle S, Aricò G, Panarello F, Spadaro A, Pasquinucci L, Pappalardo MS, Parenti C, Ronsisvalle N.
Ronsisvalle S, et al. Among authors: panarello f.
Bioorg Med Chem. 2016 Nov 1;24(21):5280-5290. doi: 10.1016/j.bmc.2016.08.057. Epub 2016 Aug 30.
Bioorg Med Chem. 2016.
PMID: 27624520
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Pharmacological properties and biochemical mechanisms of μ-opioid receptor ligands might be due to different binding poses: MD studies.
Ronsisvalle S, Panarello F, Spadaro A, Franchini S, Pappalardo M, Guccione S, Basile L.
Ronsisvalle S, et al. Among authors: panarello f.
Future Med Chem. 2020 Nov;12(22):2001-2018. doi: 10.4155/fmc-2020-0249. Epub 2020 Sep 25.
Future Med Chem. 2020.
PMID: 32972243
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Anti-malarial Drugs are Not Created Equal for SARS-CoV-2 Treatment: A Computational Analysis Evidence.
Ronsisvalle S, Panarello F, Di Mauro R, Bernardini R, Volti GL, Cantarella G.
Ronsisvalle S, et al. Among authors: panarello f.
Curr Pharm Des. 2021;27(10):1323-1329. doi: 10.2174/1381612826666201210092736.
Curr Pharm Des. 2021.
PMID: 33302855
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Role of Iron Chelation and Protease Inhibition of Natural Products on COVID-19 Infection.
Carota G, Ronsisvalle S, Panarello F, Tibullo D, Nicolosi A, Li Volti G.
Carota G, et al. Among authors: panarello f.
J Clin Med. 2021 May 25;10(11):2306. doi: 10.3390/jcm10112306.
J Clin Med. 2021.
PMID: 34070628
Free PMC article.
Review.
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Renal sodium handling in patients with normal pressure glaucoma.
Pechere-Bertschi A, Sunaric-Megevand G, Haefliger I, Panarello F, Maillard M, Burnier M.
Pechere-Bertschi A, et al. Among authors: panarello f.
Clin Sci (Lond). 2007 Jun;112(6):337-44. doi: 10.1042/CS20060082.
Clin Sci (Lond). 2007.
PMID: 17014421
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