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Cancer-associated fibroblasts potentiate colorectal cancer progression by crosstalk of the IGF2-IGF1R and Hippo-YAP1 signaling pathways.
Zhang J, Chen B, Li H, Wang Y, Liu X, Wong KY, Chan WN, Chan AK, Cheung AH, Leung KT, Dong Y, Pan Y, Ke H, Liang L, Zhou Z, Xiao J, Wong CC, Wu WK, Cheng AS, Ma BB, Yu J, Lo KW, Kang W; Ka Fai To. Zhang J, et al. Among authors: pan y. J Pathol. 2023 Feb;259(2):205-219. doi: 10.1002/path.6033. Epub 2022 Dec 17. J Pathol. 2023. PMID: 36373776
FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.
Zhang J, Zhou Y, Huang T, Wu F, Pan Y, Dong Y, Wang Y, Chan AKY, Liu L, Kwan JSH, Cheung AHK, Wong CC, Lo AKF, Cheng ASL, Yu J, Lo KW, Kang W, To KF. Zhang J, et al. Among authors: pan y. Oncogene. 2019 Jan;38(1):33-46. doi: 10.1038/s41388-018-0430-x. Epub 2018 Aug 6. Oncogene. 2019. PMID: 30082912 Free PMC article.
STK3 promotes gastric carcinogenesis by activating Ras-MAPK mediated cell cycle progression and serves as an independent prognostic biomarker.
Chen B, Chan WN, Mui CW, Liu X, Zhang J, Wang Y, Cheung AHK, Chan AKY, Chan RCK, Leung KT, Dong Y, Pan Y, Ke H, Liang L, Zhou Z, Wong CC, Wu WKK, Cheng ASL, Yu J, Lo KW, To KF, Kang W. Chen B, et al. Among authors: pan y. Mol Cancer. 2021 Nov 12;20(1):147. doi: 10.1186/s12943-021-01451-2. Mol Cancer. 2021. PMID: 34772410 Free PMC article. No abstract available.
Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.
Yu J, Wu WK, Li X, He J, Li XX, Ng SS, Yu C, Gao Z, Yang J, Li M, Wang Q, Liang Q, Pan Y, Tong JH, To KF, Wong N, Zhang N, Chen J, Lu Y, Lai PB, Chan FK, Li Y, Kung HF, Yang H, Wang J, Sung JJ. Yu J, et al. Among authors: pan y. Gut. 2015 Apr;64(4):636-45. doi: 10.1136/gutjnl-2013-306620. Epub 2014 Jun 20. Gut. 2015. PMID: 24951259 Free PMC article.
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