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Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction.
J Med Chem. 2022 Dec 22;65(24):16818-16828. doi: 10.1021/acs.jmedchem.2c01635. Epub 2022 Dec 9.
J Med Chem. 2022.
PMID: 36484727
Free PMC article.
Correction to "Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction".
Pallesen JS, Munier CC, Bosica F, Andrei SA, Edman K, Gunnarsson A, La Sala G, Putra OD, Srdanović S, Wilson AJ, Wissler L, Ottmann C, Perry MWD, O'Mahony G.
Pallesen JS, et al.
J Med Chem. 2023 Feb 9;66(3):2205-2207. doi: 10.1021/acs.jmedchem.3c00076. Epub 2023 Jan 28.
J Med Chem. 2023.
PMID: 36708352
Free PMC article.
No abstract available.
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Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
Pallesen JS, Narayanan D, Tran KT, Solbak SMØ, Marseglia G, Sørensen LME, Høj LJ, Munafò F, Carmona RMC, Garcia AD, Desu HL, Brambilla R, Johansen TN, Popowicz GM, Sattler M, Gajhede M, Bach A.
Pallesen JS, et al.
J Med Chem. 2021 Apr 22;64(8):4623-4661. doi: 10.1021/acs.jmedchem.0c02094. Epub 2021 Apr 5.
J Med Chem. 2021.
PMID: 33818106
Free article.
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Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery.
Narayanan D, Tran KT, Pallesen JS, Solbak SMØ, Qin Y, Mukminova E, Luchini M, Vasilyeva KO, González Chichón D, Goutsiou G, Poulsen C, Haapanen N, Popowicz GM, Sattler M, Olagnier D, Gajhede M, Bach A.
Narayanan D, et al. Among authors: pallesen js.
J Med Chem. 2022 Nov 10;65(21):14481-14526. doi: 10.1021/acs.jmedchem.2c00830. Epub 2022 Oct 20.
J Med Chem. 2022.
PMID: 36263945
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A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity.
Tran KT, Pallesen JS, Solbak SMØ, Narayanan D, Baig A, Zang J, Aguayo-Orozco A, Carmona RMC, Garcia AD, Bach A.
Tran KT, et al. Among authors: pallesen js.
J Med Chem. 2019 Sep 12;62(17):8028-8052. doi: 10.1021/acs.jmedchem.9b00723. Epub 2019 Aug 27.
J Med Chem. 2019.
PMID: 31411465
Free article.
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Non-covalent Small-Molecule Kelch-like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Inhibitors and Their Potential for Targeting Central Nervous System Diseases.
Pallesen JS, Tran KT, Bach A.
Pallesen JS, et al.
J Med Chem. 2018 Sep 27;61(18):8088-8103. doi: 10.1021/acs.jmedchem.8b00358. Epub 2018 May 29.
J Med Chem. 2018.
PMID: 29750408
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N-Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28-Let-7 Interaction.
Borgelt L, Hohnen L, Pallesen JS, Hommen P, Goebel GL, Bosica F, Liu Y, O'Mahony G, Wu P.
Borgelt L, et al. Among authors: pallesen js.
ACS Med Chem Lett. 2023 Nov 14;14(12):1707-1715. doi: 10.1021/acsmedchemlett.3c00341. eCollection 2023 Dec 14.
ACS Med Chem Lett. 2023.
PMID: 38116413
Free PMC article.
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